Technology Process of C16H14N2O3
There total 5 articles about C16H14N2O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 1.5 h / -78 °C / Inert atmosphere
1.2: 1 h / -78 °C / Inert atmosphere
2.1: chromium(VI) oxide; pyridine / dichloromethane / 4 h / 20 °C / Inert atmosphere
3.1: bis-triphenylphosphine-palladium(II) chloride; triphenylphosphine; triethylamine / tetrahydrofuran / 0.33 h / 20 °C / Inert atmosphere
3.2: 20 °C / Inert atmosphere
4.1: potassium carbonate / methanol / 0.5 h / 0 °C / Inert atmosphere
With
pyridine; chromium(VI) oxide; bis-triphenylphosphine-palladium(II) chloride; potassium carbonate; triethylamine; triphenylphosphine; lithium diisopropyl amide;
In
tetrahydrofuran; methanol; hexane; dichloromethane;
3.1: |Sonogashira Cross-Coupling / 3.2: |Sonogashira Cross-Coupling;
DOI:10.1016/j.tetlet.2013.01.005
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: chromium(VI) oxide; pyridine / dichloromethane / 4 h / 20 °C / Inert atmosphere
2.1: bis-triphenylphosphine-palladium(II) chloride; triphenylphosphine; triethylamine / tetrahydrofuran / 0.33 h / 20 °C / Inert atmosphere
2.2: 20 °C / Inert atmosphere
3.1: potassium carbonate / methanol / 0.5 h / 0 °C / Inert atmosphere
With
pyridine; chromium(VI) oxide; bis-triphenylphosphine-palladium(II) chloride; potassium carbonate; triethylamine; triphenylphosphine;
In
tetrahydrofuran; methanol; dichloromethane;
2.1: |Sonogashira Cross-Coupling / 2.2: |Sonogashira Cross-Coupling;
DOI:10.1016/j.tetlet.2013.01.005