5-(Cyclohexylamino)pentan-1-ol

Base Information

• Chemical Name: 5-(Cyclohexylamino)pentan-1-ol
• CAS No.: 6951-34-4
• Molecular Formula: C11H23 N O
• Molecular Weight: 185.3064
• NSC Number: 55127
• DSSTox Substance ID: DTXSID40288264
• Wikidata: Q82024595
• Mol file: 6951-34-4.mol

Synonyms:6951-34-4;5-(cyclohexylamino)pentan-1-ol;NSC55127;DTXSID40288264;NSC-55127;AKOS011511458

Chemical Property of 5-(Cyclohexylamino)pentan-1-ol

Chemical Property:

• Vapor Pressure: 0.000135mmHg at 25°C
• Boiling Point: 297.6°Cat760mmHg
• Flash Point: 90°C
• Density: 0.93g/cm³
• XLogP3: 2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 185.177964357
• Heavy Atom Count: 13
• Complexity: 111

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(CC1)NCCCCCO

Technology Process of 5-(Cyclohexylamino)pentan-1-ol

There total 8 articles about 5-(Cyclohexylamino)pentan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

1-(5-Hydroxy-pentylamino)-cyclohexanecarbonitrile → 5-(cyclohexylamino)pentan-1-ol (6951-34-4)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; Hg(II) trifluoroacetate; sodium cyanoborohydride; In methanol; for 24h; Ambient temperature;

DOI:10.1016/0040-4020(96)00631-X

Reference yield: 60.0%

5-chloropentan-1-ol (5259-98-3) + cyclohexylamine (108-91-8,157973-60-9) → 5-(cyclohexylamino)pentan-1-ol (6951-34-4)

Guidance literature:

In methanol; for 18h; Reflux;

DOI:10.1039/c6cc02178f

Reference yield:

5-hydroxypentanal (4221-03-8) + cyclohexylamine (108-91-8,157973-60-9) → 5-(cyclohexylamino)pentan-1-ol (6951-34-4)

Guidance literature:

With hydrogenchloride; platinum; under 102971 Torr; Hydrogenation;

DOI:10.1021/ja01170a023

upstream raw materials:

cyclohexyl-tetrahydropyran-2-yl-amine

5-hydroxypentanal

cyclohexylamine

cyclohexyl-tetrahydropyran-2-ylidene-amine

Downstream raw materials:

N-Cyclohexyl-4-(3-formyl-4-nitro-phenoxy)-N-(5-hydroxy-pentyl)-butyramide

5-(1-Phenyl-cyclohexylamino)-pentan-1-ol

N-Cyclohexyl-N-(5-hydroxy-pentyl)-4-(2-oxo-1,2,3,5-tetrahydro-imidazo[2,1-b]quinazolin-7-yloxy)-butyramide

5-pentanoic acid