Chemical Property of Arbekacin
Chemical Property:
- Vapor Pressure:0mmHg at 25°C
- Refractive Index:1.634
- Boiling Point:904 °C at 760 mmHg
- PKA:13.07±0.70(Predicted)
- Flash Point:500.5 °C
- Density:1.47 g/cm3
- XLogP3:-6.8
- Hydrogen Bond Donor Count:11
- Hydrogen Bond Acceptor Count:15
- Rotatable Bond Count:10
- Exact Mass:552.31189162
- Heavy Atom Count:38
- Complexity:757
- Purity/Quality:
-
99% *data from raw suppliers
ARBEKACIN 95.00% *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:C1CC(C(OC1CN)OC2C(CC(C(C2O)OC3C(C(C(C(O3)CO)O)N)O)NC(=O)C(CCN)O)N)N
- Isomeric SMILES:C1C[C@H]([C@H](O[C@@H]1CN)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)N)O)NC(=O)[C@H](CCN)O)N)N
- Recent ClinicalTrials:Phase II Study of NPC-14 (Arbekacin Sulfate) to Explore Safety, Tolerability, and Efficacy in Duchenne Muscular Dystrophy
- Recent NIPH Clinical Trials:The efficacy of AN69 membrane for elimination of aminoglycoside.
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Description
Arbekacin is a semi-synthetic derivative of dibekacin useful in the treatment of
bacterial infections. This aminoglycoside is active against a broad spectrum of
bacteria, including some of the gentamycin-, kanamycin-, and tobramycin-resistant
pathogens. Compared to amikacin and dibekacin, ototoxicity is reportedly milder.
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Therapeutic Function
Antibiotic
