N-{5-[(benzo[d]thiazol-2-ylsulfonyl)methyl]-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl}-N-methylmethanesulfonamide

Base Information

Chemical Name:N-{5-[(benzo[d]thiazol-2-ylsulfonyl)methyl]-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl}-N-methylmethanesulfonamide
CAS No.:1234331-55-5
Molecular Formula:C₂₃H₂₃FN₄O₄S₃
Molecular Weight:534.656
Hs Code.:

Synonyms:N-{5-[(benzo[d]thiazol-2-ylsulfonyl)methyl]-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl}-N-methylmethanesulfonamide

Suppliers and Price of N-{5-[(benzo[d]thiazol-2-ylsulfonyl)methyl]-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl}-N-methylmethanesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-{5-[(benzo[d]thiazol-2-ylsulfonyl)methyl]-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl}-N-methylmethanesulfonamide

Chemical Property:

Purity/Quality:: 90%，95%，97%，98%，99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-{5-[(benzo[d]thiazol-2-ylsulfonyl)methyl]-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl}-N-methylmethanesulfonamide

There total 1 articles about N-{5-[(benzo[d]thiazol-2-ylsulfonyl)methyl]-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl}-N-methylmethanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 1234331-53-3
N-{5-[(benzo[d]thiazol-2-ylthio)methyl]-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl}-N-methylmethanesulfonamide

: 1234331-55-5
N-{5-[(benzo[d]thiazol-2-ylsulfonyl)methyl]-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl}-N-methylmethanesulfonamide

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; for 12h;

Reference yield: 83.0%

: 915749-98-3
(4R-cis)-6-formyl-2,2-dimethyl-1,3-dioxane-4-acetic acid ethyl ester

: 1234331-55-5
N-{5-[(benzo[d]thiazol-2-ylsulfonyl)methyl]-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl}-N-methylmethanesulfonamide

: 851440-18-1
6-((1E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(methyl(methylsulfonyl)amino)pyrimidin-5-yl)ethenyl)-2,2-dimethyl-1,3-dioxan-4yl acetic acid ethyl ester

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; at -30 ℃; Product distribution / selectivity;

Reference yield: 66.0%

: (2S,4R)-4-(tert-butyldimethylsilyloxy)-6-oxotetrahydro-2H-pyran-2-carboxaldehyde

: 1234331-55-5
N-{5-[(benzo[d]thiazol-2-ylsulfonyl)methyl]-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl}-N-methylmethanesulfonamide

: N-(5-((E)-2-((2S,4R)-4-(tert-butyldimethylsilyloxy)-6-oxotetrahydro-2H-pyran-2-yl)vinyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide

: 934-34-9
2-hydroxybenzothiazole

Guidance literature:: With potassium hexamethylsilazane; In tetrahydrofuran; at -60 ℃; Concentration; Reagent/catalyst; Temperature; Inert atmosphere;
DOI:10.1055/s-0033-1338648