Diethyl ({[4-(benzyloxy)phenyl]amino}methylidene)propanedioate

Base Information

Chemical Name:Diethyl ({[4-(benzyloxy)phenyl]amino}methylidene)propanedioate
CAS No.:6093-78-3
Molecular Formula:C21H23NO5
Molecular Weight:369.411
Hs Code.:
DSSTox Substance ID:DTXSID30367456
Nikkaji Number:J665.039B

Synonyms:6093-78-3;ST51014849;CBMicro_045423;SCHEMBL10861049;DTXSID30367456;diethyl ({[4-(benzyloxy)phenyl]amino}methylidene)propanedioate;STK083312;AKOS003230321;BIM-0045297.P001;[[4-(Benzyloxy)anilino]methylene]malonic acid diethyl ester

Suppliers and Price of Diethyl ({[4-(benzyloxy)phenyl]amino}methylidene)propanedioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Diethyl ({[4-(benzyloxy)phenyl]amino}methylidene)propanedioate

Chemical Property:

Vapor Pressure:4.78E-09mmHg at 25°C
Boiling Point:471.1°Cat760mmHg
Flash Point:238.7°C
Density:1.193g/cm³
XLogP3:4.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:11
Exact Mass:369.15762283
Heavy Atom Count:27
Complexity:471

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(=CNC1=CC=C(C=C1)OCC2=CC=CC=C2)C(=O)OCC

Technology Process of Diethyl ({[4-(benzyloxy)phenyl]amino}methylidene)propanedioate

There total 2 articles about Diethyl ({[4-(benzyloxy)phenyl]amino}methylidene)propanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.6%

: 14382-91-3
2-hydroxy-4,5-dimethoxybenzaldehyde

: 105-53-3
diethyl malonate

: 6093-78-3
ethyl 6,7-dimethoxy-2-oxo-2H-chromene-3-carboxylate

Guidance literature:: With piperidine; acetic acid; In ethanol; Reflux;
DOI:10.1016/j.molstruc.2022.132576

Reference yield:

: 2033-89-8
3,4-dimethoxyphenol

: 6093-78-3
ethyl 6,7-dimethoxy-2-oxo-2H-chromene-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: magnesium chloride; triethylamine / acetonitrile / Reflux

2: piperidine; acetic acid / ethanol / Reflux

With piperidine; acetic acid; triethylamine; magnesium chloride; In ethanol; acetonitrile;
DOI:10.1016/j.molstruc.2022.132576