C₂₇H₂₇NO₆

Base Information

Chemical Name:C₂₇H₂₇NO₆
CAS No.:1421015-74-8
Molecular Formula:C₂₇H₂₇NO₆
Molecular Weight:461.514
Hs Code.:

C<sub>27</sub>H<sub>27</sub>NO<sub>6</sub>

Synonyms:C₂₇H₂₇NO₆

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Chemical Property of C₂₇H₂₇NO₆

Chemical Property:

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Technology Process of C₂₇H₂₇NO₆

There total 4 articles about C₂₇H₂₇NO₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1427443-06-8
ethyl N-{7-[4-hydroxy-3-(1-hydroxy-2-phenylethyl)phenoxy]-6-methylindan-4-yl}malonamate

: 1421015-74-8
C₂₇H₂₇NO₆

Guidance literature:: With water; sodium hydroxide; In methanol; at 60 ℃; for 0.5h; Inert atmosphere;
DOI:10.1016/j.bmc.2012.12.002

Reference yield:

: 575505-01-0
[7-(4-methoxyphenoxy)-6-methylindan-4-yl]amine

: 1421015-74-8
C₂₇H₂₇NO₆

Guidance literature:: Multi-step reaction with 5 steps

1: pyridine / dichloromethane / 3 h / 20 °C

2: trifluoromethylsulfonic anhydride / dichloromethane / 15 h / 20 °C

3: boron trichloride / dichloromethane / 0 - 20 °C

4: sodium tris(acetoxy)borohydride / tetrahydrofuran / 20 °C

5: water; sodium hydroxide / methanol / 0.5 h / 60 °C / Inert atmosphere

With pyridine; trifluoromethylsulfonic anhydride; water; boron trichloride; sodium tris(acetoxy)borohydride; sodium hydroxide; In tetrahydrofuran; methanol; dichloromethane; 2: |Friedel-Crafts Acylation;
DOI:10.1016/j.bmc.2012.12.002

Reference yield:

: 575504-26-6
5-methyl-7-nitroindan-4-ol

: 1421015-74-8
C₂₇H₂₇NO₆

Guidance literature:: Multi-step reaction with 7 steps

1: copper; triethylamine / dichloromethane / 120 h / 20 °C

2: palladium 10% on activated carbon; hydrogen / ethyl acetate / 20 °C

3: pyridine / dichloromethane / 3 h / 20 °C

4: trifluoromethylsulfonic anhydride / dichloromethane / 15 h / 20 °C

5: boron trichloride / dichloromethane / 0 - 20 °C

6: sodium tris(acetoxy)borohydride / tetrahydrofuran / 20 °C

7: water; sodium hydroxide / methanol / 0.5 h / 60 °C / Inert atmosphere

With pyridine; trifluoromethylsulfonic anhydride; palladium 10% on activated carbon; water; hydrogen; boron trichloride; sodium tris(acetoxy)borohydride; copper; triethylamine; sodium hydroxide; In tetrahydrofuran; methanol; dichloromethane; ethyl acetate; 4: |Friedel-Crafts Acylation;
DOI:10.1016/j.bmc.2012.12.002