7-Methylcoumarin

Base Information

Chemical Name:7-Methylcoumarin
CAS No.:2445-83-2
Molecular Formula:C10H8 O2
Molecular Weight:160.172
Hs Code.:2932209090
European Community (EC) Number:219-499-3
NSC Number:19511
UNII:YCN83T03QU
DSSTox Substance ID:DTXSID0062424
Nikkaji Number:J118.426A
Wikidata:Q27294453
Metabolomics Workbench ID:74348
ChEMBL ID:CHEMBL346541
Mol file:2445-83-2.mol

Synonyms:7-methylcoumarin

Suppliers and Price of 7-Methylcoumarin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-Methylcoumarin
10g
$ 50.00

TRC
7-Methylcoumarin
25g
$ 100.00

TCI Chemical
7-Methylcoumarin >98.0%(GC)
25g
$ 215.00

SynQuest Laboratories
7-Methylcoumarin 98%
10 g
$ 45.00

SynQuest Laboratories
7-Methylcoumarin 98%
2 g
$ 25.00

SynQuest Laboratories
7-Methylcoumarin 98%
25 g
$ 90.00

Sigma-Aldrich
7-Methylcoumarin ≥98%
10g
$ 129.00

Sigma-Aldrich
7-Methylcoumarin analytical standard
100mg
$ 59.60

Matrix Scientific
7-Methyl-2H-chromen-2-one 97%
1g
$ 47.00

Matrix Scientific
7-Methyl-2H-chromen-2-one 97%
10g
$ 110.00

Total 37 raw suppliers

Chemical Property of 7-Methylcoumarin

Chemical Property:

Vapor Pressure:0.000508mmHg at 25°C
Melting Point:128-130 °C(lit.)
Refractive Index:1.5300 (estimate)
Boiling Point:171-172 °C11 mm Hg(lit.)
Flash Point:125.9°C
PSA：30.21000
Density:1.2g/cm³
LogP:2.10140
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:160.052429494
Heavy Atom Count:12
Complexity:220

Purity/Quality:

99%, ^*data from raw suppliers

7-Methylcoumarin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 23/24/25
Safety Statements: 1-13-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(C=C1)C=CC(=O)O2
Uses 7-Methylcoumarin (cas# 2445-83-2) is a compound useful in organic synthesis. 7-Methylcoumarin was used as internal standard during the simultaneous determination of furocoumarin compounds in rat plasma by HPLC. 7-Methylcoumarin may be used as an analytical standard for the determination of the analyte in cosmetics, tobacco products, and plant extracts by liquid chromatography (LC) based techniques.

Technology Process of 7-Methylcoumarin

There total 43 articles about 7-Methylcoumarin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 698-27-1
4-methylsalicylaldehyde

: 108-24-7
acetic anhydride

: 2445-83-2
7-methylcoumarin

Guidance literature:: With polyphosphoric acid; In N,N-dimethyl-formamide; at 145 ℃; for 3h; Inert atmosphere;
DOI:10.1080/00397911.2020.1792498

Reference yield: 91.0%

: 115560-73-1
3-Hydroxy-3-(2-methoxymethoxy-4-methyl-phenyl)-N,N-dimethyl-propionamide

: 2445-83-2
7-methylcoumarin

Guidance literature:: With acetic acid; for 6h; Heating;
DOI:10.1021/jo00252a011

Reference yield: 81.0%

: 122-46-3
3-acetoxytoluene

: 292638-85-8,9003-21-8,96-33-3
acrylic acid methyl ester

: 2445-83-2
7-methylcoumarin

Guidance literature:: With formic acid; rhodium(II) acetate dimer; sodium acetate; In neat (no solvent); at 100 ℃; for 8h; regioselective reaction; Molecular sieve; Inert atmosphere;
DOI:10.1021/acs.joc.5b01713