[4-(1-aza-15-crown-5)phenyl]-(4,5-dimethoxy-2-nitrophenyl)-methanone

Base Information

• Chemical Name: [4-(1-aza-15-crown-5)phenyl]-(4,5-dimethoxy-2-nitrophenyl)-methanone
• CAS No.: 1160928-59-5
• Molecular Formula: C₂₅H₃₂N₂O₉
• Molecular Weight: 504.537
• Mol file: 1160928-59-5.mol

Synonyms:[4-(1-aza-15-crown-5)phenyl]-(4,5-dimethoxy-2-nitrophenyl)-methanone

Chemical Property of [4-(1-aza-15-crown-5)phenyl]-(4,5-dimethoxy-2-nitrophenyl)-methanone

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of [4-(1-aza-15-crown-5)phenyl]-(4,5-dimethoxy-2-nitrophenyl)-methanone

There total 1 articles about [4-(1-aza-15-crown-5)phenyl]-(4,5-dimethoxy-2-nitrophenyl)-methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.6%

(4-bromophenyl)( 4,5-dimethoxy-2-nitrophenyl)-methanone (886493-86-3) + 1,4,7,10-tetraoxa-15-azacyclopentadecane (66943-05-3) → [4-(1-aza-15-crown-5)phenyl]-(4,5-dimethoxy-2-nitrophenyl)-methanone (1160928-59-5)

Guidance literature:

With oxygen; palladium diacetate; triphenylphosphine; sodium t-butanolate; In toluene; at 100 ℃; for 24h; Inert atmosphere;

DOI:10.1021/ol900902z

Reference yield: 12.0%

[4-(1-aza-15-crown-5)phenyl]-(4,5-dimethoxy-2-nitrophenyl)-methanone (1160928-59-5) → [4-(1,4,7,10-tetraoxa-13-azacyclopentadec-13-yl)phenyl](4,5-dimethoxy-2-nitrophenyl)methanol (1160928-60-8)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 20 ℃; for 0.5h;

DOI:10.1021/ol900902z

upstream raw materials:

(4-bromophenyl)( 4,5-dimethoxy-2-nitrophenyl)-methanone

1,4,7,10-tetraoxa-15-azacyclopentadecane

Downstream raw materials:

[4-(1,4,7,10-tetraoxa-13-azacyclopentadec-13-yl)phenyl](4,5-dimethoxy-2-nitrophenyl)methanol