Ethyl 4-[2,2-Dimethyl-5-(toluene-4-sulfonyl)tetrahydro[1,3]dioxolo[4,5-c]pyrrol-4-yl]-4-triisopropylsilyloxybutyrate

Base Information

Chemical Name:Ethyl 4-[2,2-Dimethyl-5-(toluene-4-sulfonyl)tetrahydro[1,3]dioxolo[4,5-c]pyrrol-4-yl]-4-triisopropylsilyloxybutyrate
CAS No.:253778-08-4
Molecular Formula:C₂₉H₄₉NO₇SSi
Molecular Weight:583.862
Hs Code.:

Synonyms:Ethyl 4-[2,2-Dimethyl-5-(toluene-4-sulfonyl)tetrahydro[1,3]dioxolo[4,5-c]pyrrol-4-yl]-4-triisopropylsilyloxybutyrate

Suppliers and Price of Ethyl 4-[2,2-Dimethyl-5-(toluene-4-sulfonyl)tetrahydro[1,3]dioxolo[4,5-c]pyrrol-4-yl]-4-triisopropylsilyloxybutyrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Ethyl 4-[2,2-Dimethyl-5-(toluene-4-sulfonyl)tetrahydro[1,3]dioxolo[4,5-c]pyrrol-4-yl]-4-triisopropylsilyloxybutyrate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Ethyl 4-[2,2-Dimethyl-5-(toluene-4-sulfonyl)tetrahydro[1,3]dioxolo[4,5-c]pyrrol-4-yl]-4-triisopropylsilyloxybutyrate

There total 4 articles about Ethyl 4-[2,2-Dimethyl-5-(toluene-4-sulfonyl)tetrahydro[1,3]dioxolo[4,5-c]pyrrol-4-yl]-4-triisopropylsilyloxybutyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 253778-07-3
Ethyl (E)-4-[2,2-dimethyl-5-(toluene-4-sulfonyl)tetrahydro[1,3]dioxolo[4,5-c]pyrrol-4-yl]-4-triisopropylsilyloxy-2-butenoate

: 253778-08-4
Ethyl 4-[2,2-Dimethyl-5-(toluene-4-sulfonyl)tetrahydro[1,3]dioxolo[4,5-c]pyrrol-4-yl]-4-triisopropylsilyloxybutyrate

Guidance literature:: With hydrogen; platinum(IV) oxide; In ethanol; at 20 ℃; for 1.5h; under 760 Torr;
DOI:10.1002/(SICI)1521-3765(19991105)5:11<3279::AID-CHEM3279>3.0.CO;2-4

Reference yield:

: 253778-04-0
[2,2-Dimethyl-5-(toluene-4-sulfonyl)tetrahydro[1,3]dioxolo[4,5-c]pyrrol-4-yl]-2-triisopropylsilyloxyacetaldehyde

: 253778-08-4
Ethyl 4-[2,2-Dimethyl-5-(toluene-4-sulfonyl)tetrahydro[1,3]dioxolo[4,5-c]pyrrol-4-yl]-4-triisopropylsilyloxybutyrate

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / LiCl; DBU / acetonitrile / 2 h / 20 °C

2: 99 percent / H₂ / PtO₂ / ethanol / 1.5 h / 20 °C / 760 Torr

With hydrogen; 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride; platinum(IV) oxide; In ethanol; acetonitrile; 1: Condensation / 2: Catalytic hydrogenation;
DOI:10.1002/(SICI)1521-3765(19991105)5:11<3279::AID-CHEM3279>3.0.CO;2-4

Reference yield:

: 253778-03-9
2-[2,2-Dimethyl-5-(toluene-4-sulfonyl)tetrahydro[1,3]dioxolo[4,5-c]pyrrol-4-yl]-2-triisopropylsilyloxyethanol

: 253778-08-4
Ethyl 4-[2,2-Dimethyl-5-(toluene-4-sulfonyl)tetrahydro[1,3]dioxolo[4,5-c]pyrrol-4-yl]-4-triisopropylsilyloxybutyrate

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / Dess-Martin periodinane; NaHCO₃ / CH₂Cl₂ / 0.75 h / 20 °C

2: 90 percent / LiCl; DBU / acetonitrile / 2 h / 20 °C

3: 99 percent / H₂ / PtO₂ / ethanol / 1.5 h / 20 °C / 760 Torr

With hydrogen; sodium hydrogencarbonate; Dess-Martin periodane; 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride; platinum(IV) oxide; In ethanol; dichloromethane; acetonitrile; 1: Oxidation / 2: Condensation / 3: Catalytic hydrogenation;
DOI:10.1002/(SICI)1521-3765(19991105)5:11<3279::AID-CHEM3279>3.0.CO;2-4