N-(1,3-benzodioxol-5-ylmethyl)-2-(3,4-dimethoxyphenyl)ethanamine

Base Information

• Chemical Name: N-(1,3-benzodioxol-5-ylmethyl)-2-(3,4-dimethoxyphenyl)ethanamine
• CAS No.: 111355-37-4
• Molecular Formula: C₁₈H₂₁NO₄
• Molecular Weight: 315.369
• Mol file: 111355-37-4.mol

Synonyms:N-(3,4-methylenedioxybenzyl)-3,4-dimethoxyphenylethylamine

Chemical Property of N-(1,3-benzodioxol-5-ylmethyl)-2-(3,4-dimethoxyphenyl)ethanamine

Chemical Property:

Purity/Quality:

N-(1,3-BENZODIOXOL-5-YLMETHYL)-2-(3,4-DIMETHOXYPHENYL)ETHANAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(1,3-benzodioxol-5-ylmethyl)-2-(3,4-dimethoxyphenyl)ethanamine

There total 6 articles about N-(1,3-benzodioxol-5-ylmethyl)-2-(3,4-dimethoxyphenyl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(3,4-methylenedioxybenzylidene)homoveratrylamine (119520-75-1) → N-(3,4-methylenedioxybenzyl)-3,4-dimethoxyphenylethylamine (111355-37-4)

Guidance literature:

With 1,4-dioxane; nickel; Hydrogenation;

DOI:10.1039/jr9550003926

Reference yield:

2-(3,4-dimethoxyphenyl)-ethylamine (120-20-7) → N-(3,4-methylenedioxybenzyl)-3,4-dimethoxyphenylethylamine (111355-37-4)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene / Heating

2: NaBH₄ / methanol / 0 - 5 °C

With sodium tetrahydroborate; In methanol; benzene;

DOI:10.1007/BF00630535

Reference yield:

piperonal (120-57-0,30024-74-9) → N-(3,4-methylenedioxybenzyl)-3,4-dimethoxyphenylethylamine (111355-37-4)

Guidance literature:

Multi-step reaction with 2 steps

2: platinum; acetic acid / Hydrogenation

With acetic acid; platinum;

DOI:10.1021/ja01357a023

upstream raw materials:

N-(3,4-methylenedioxybenzylidene)homoveratrylamine

piperonal

2-(3,4-dimethoxyphenyl)-ethylamine

N-(3,4-dimethoxyphenethyl)-3,4-methylenedioxybenzamide