2,6-Dibromo-3,4-dimethylaniline

Base Information

• Chemical Name: 2,6-Dibromo-3,4-dimethylaniline
• CAS No.: 80948-77-2
• Molecular Formula: C₈H₉Br₂N
• Molecular Weight: 278.974
• DSSTox Substance ID: DTXSID70554909
• Nikkaji Number: J257.636H
• Wikidata: Q82436093
• Mol file: 80948-77-2.mol

Synonyms:2,6-Dibromo-3,4-dimethylaniline;80948-77-2;SCHEMBL11067091;DTXSID70554909;AKOS026672253;FS-4170

Chemical Property of 2,6-Dibromo-3,4-dimethylaniline

Chemical Property:

• Melting Point: 60-63°C
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 278.90813
• Heavy Atom Count: 11
• Complexity: 140

Purity/Quality:

2,6-Dibromo-3,4-dimethylaniline 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC(=C(C(=C1C)Br)N)Br

Technology Process of 2,6-Dibromo-3,4-dimethylaniline

There total 4 articles about 2,6-Dibromo-3,4-dimethylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-amino-o-xylene (95-64-7) → 2,6-dibromo-3,4-dimethyl-aniline (80948-77-2)

Guidance literature:

With benzyltrimethylammonium tribromide; calcium carbonate; In methanol; dichloromethane; for 0.5h; Ambient temperature;

DOI:10.1246/bcsj.61.597

Reference yield:

acetic acid (64-19-7,77671-22-8) + 4-amino-o-xylene (95-64-7) → 2,6-dibromo-3,4-dimethyl-aniline (80948-77-2)

Guidance literature:

Bromierung;

Reference yield:

toluene-4-sulfonic acid-(2,6-dibromo-3,4-dimethyl-anilide) → 2,6-dibromo-3,4-dimethyl-aniline (80948-77-2)

Guidance literature:

With sulfuric acid;

DOI:10.1039/jr9550002376

upstream raw materials:

acetic acid

4-amino-o-xylene

N-(3,4-dimethylphenyl)-4-methylbenzenesulfonamide