N-(Adamantan-1-yl)-4-bromobenzamide

Base Information

Chemical Name:N-(Adamantan-1-yl)-4-bromobenzamide
CAS No.:403845-70-5
Molecular Formula:C₁₇H₂₀BrNO
Molecular Weight:334.256
Hs Code.:
DSSTox Substance ID:DTXSID50403486
Wikidata:Q82207167
Mol file:403845-70-5.mol

Synonyms:N-(Adamantan-1-yl)-4-bromobenzamide;403845-70-5;N-(1-adamantyl)-4-bromobenzamide;Oprea1_666805;DTXSID50403486;AKOS000202682;(z)-N-(adamantan-1-yl)-4-bromobenzamide

Suppliers and Price of N-(Adamantan-1-yl)-4-bromobenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
N-(Adamantan-1-yl)-4-bromobenzamide 95+%
1g
$ 772.00

Chemenu
N-(Adamantan-1-yl)-4-bromobenzamide 95%
1g
$ 729.00

Alichem
N-(Adamantan-1-yl)-4-bromobenzamide
1g
$ 634.28

Total 3 raw suppliers

Chemical Property of N-(Adamantan-1-yl)-4-bromobenzamide

Chemical Property:

XLogP3:4.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:333.07283
Heavy Atom Count:20
Complexity:359

Purity/Quality:

99% ^*data from raw suppliers

N-(Adamantan-1-yl)-4-bromobenzamide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2CC3CC1CC(C2)(C3)NC(=O)C4=CC=C(C=C4)Br

Technology Process of N-(Adamantan-1-yl)-4-bromobenzamide

There total 2 articles about N-(Adamantan-1-yl)-4-bromobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 768-95-6
1-adamanthanol

: 623-00-7
4-bromobenzenecarbonitrile

: 403845-70-5
(Z)-N-(adamantan-1-yl)-4-bromobenzamide

Guidance literature:: 1-adamanthanol; 4-bromobenzenecarbonitrile; for 17h; Inert atmosphere; Heating;

With water; Inert atmosphere;
DOI:10.1016/j.tetlet.2020.152553

Reference yield:

: 1122-91-4
4-bromo-benzaldehyde

: 403845-70-5
(Z)-N-(adamantan-1-yl)-4-bromobenzamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium azide; tetrafluoroboric acid diethyl ether; acetic acid / 1 h / 20 °C

2.1: tetrafluoroboric acid diethyl ether / 3 h / 20 °C

2.2: 20 °C

With tetrafluoroboric acid diethyl ether; sodium azide; acetic acid; 1.1: |Schmidt Reaction / 2.1: |Ritter Amidation;
DOI:10.1055/s-0034-1380754

Reference yield: 64.0%

: 127-19-5,116057-81-9
N,N-dimethyl acetamide

: 403845-70-5
(Z)-N-(adamantan-1-yl)-4-bromobenzamide

: C₂₁H₂₈N₂O₂

Guidance literature:: With 2,6-dimethylpyridine; [2,2]bipyridinyl; nickel(II) bromide dimethoxyethane; at 30 ℃; for 48h; regioselective reaction; Inert atmosphere; Irradiation;
DOI:10.1021/acscatal.0c05694