benzaldehyde O-(4-(2-(2,6-difluorophenyl)-4,5-dihydrooxazol-4-yl)benzyl) oxime

Base Information

Chemical Name:benzaldehyde O-(4-(2-(2,6-difluorophenyl)-4,5-dihydrooxazol-4-yl)benzyl) oxime
CAS No.:1586758-95-3
Molecular Formula:C₂₃H₁₈F₂N₂O₂
Molecular Weight:392.405
Hs Code.:

Synonyms:benzaldehyde O-(4-(2-(2,6-difluorophenyl)-4,5-dihydrooxazol-4-yl)benzyl) oxime

Suppliers and Price of benzaldehyde O-(4-(2-(2,6-difluorophenyl)-4,5-dihydrooxazol-4-yl)benzyl) oxime

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of benzaldehyde O-(4-(2-(2,6-difluorophenyl)-4,5-dihydrooxazol-4-yl)benzyl) oxime

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of benzaldehyde O-(4-(2-(2,6-difluorophenyl)-4,5-dihydrooxazol-4-yl)benzyl) oxime

There total 8 articles about benzaldehyde O-(4-(2-(2,6-difluorophenyl)-4,5-dihydrooxazol-4-yl)benzyl) oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 1586758-91-9
N-(1-(4-(bromomethyl)phenyl)-2-chloroethyl)-2,6-difluorobenzamide

: 932-90-1
Benzaldoxime

: 1586758-95-3
benzaldehyde O-(4-(2-(2,6-difluorophenyl)-4,5-dihydrooxazol-4-yl)benzyl) oxime

Guidance literature:: Benzaldoxime; With sodium hydride; In N,N-dimethyl-formamide; for 0.666667h;

N-(1-(4-(bromomethyl)phenyl)-2-chloroethyl)-2,6-difluorobenzamide; In N,N-dimethyl-formamide; at 0 ℃;
DOI:10.1021/jf500461a DOI:10.1021/jf500461a

Reference yield: 68.0%

: 1586758-95-3
benzaldehyde O-(4-(2-(2,6-difluorophenyl)-4,5-dihydrooxazol-4-yl)benzyl) oxime

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; for 0.666667h;

In N,N-dimethyl-formamide; Cooling with ice;

Reference yield:

: 5524-56-1
ethyl 2-p-tolyl-2-oxoacetate

: 1586758-95-3
benzaldehyde O-(4-(2-(2,6-difluorophenyl)-4,5-dihydrooxazol-4-yl)benzyl) oxime

Guidance literature:: Multi-step reaction with 6 steps

1.1: hydroxylamine hydrochloride / ethanol / 8 h / Reflux

2.1: sodium tetrahydroborate; iodine / tetrahydrofuran / 11.5 h / 0 °C / Reflux

2.2: 5 h / Reflux

3.1: triethylamine / tetrahydrofuran / 7.5 h / 0 - 20 °C

4.1: thionyl chloride / chloroform / 2.83 h / Reflux

5.1: potassium bromide; potassium bromate; hydrogenchloride / dichloromethane; water / 0 °C

6.1: sodium hydride / N,N-dimethyl-formamide / 0.67 h

6.2: 0 °C

With potassium bromate; hydrogenchloride; sodium tetrahydroborate; thionyl chloride; hydroxylamine hydrochloride; iodine; sodium hydride; triethylamine; potassium bromide; In tetrahydrofuran; ethanol; dichloromethane; chloroform; water; N,N-dimethyl-formamide;
DOI:10.1021/jf500461a