5524-56-1

Basic information

• Product Name: ETHYL 4-METHYLBENZOYLFORMATE
• Synonyms: (P-TOLYL)GLYOXYLIC ACID ETHYL ESTER;Oxo-p-tolyl-aceticacidethylester;ETHYL 2-(4-METHYLPHENYL)-2-OXOACETATE;ETHYL 2-(4-METHYLPHENYL)GLYOXYLATE;ETHYL 4-METHYLBENZOYLFORMATE;ETHYL 2-(4-METHYLPHENYL)-2-OXOACETATE: TECH.;4-Methyl-oxo-benzeneacetic acid ethyl ester;ethyl 2-oxo-2-p-tolylacetate
• CAS NO: 5524-56-1
• Molecular Formula: C₁₁H₁₂O₃
• Molecular Weight: 192.21
• Product Categories: Esters;Phenyls & Phenyl-Het
• Mol File: 5524-56-1.mol
• Article Data: 67

Chemical Properties

• Boiling Point: 82 °C
• Flash Point: 128.3 °C
• Appearance: /
• Density: 1.106 g/cm³
• Vapor Pressure: 0.00195mmHg at 25°C
• Refractive Index: 1.512
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: ETHYL 4-METHYLBENZOYLFORMATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 4-METHYLBENZOYLFORMATE(5524-56-1)
• EPA Substance Registry System: ETHYL 4-METHYLBENZOYLFORMATE(5524-56-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 5524-56-1(Hazardous Substances Data)

Usage

General Description

Ethyl 4-methylbenzoylformate is an organic compound that belongs to the ester family. It is a clear, colorless liquid with a fruity, floral odor. This chemical is commonly used as a flavoring agent and fragrance ingredient in the production of food, beverages, and cosmetics. Ethyl 4-methylbenzoylformate is also utilized in the synthesis of various pharmaceuticals and as an intermediate in organic chemical reactions. It is important to handle this substance with care, as it may cause irritation to the skin, eyes, and respiratory system upon contact or inhalation.

InChI:InChI=1/C11H12O3/c1-3-14-11(13)10(12)9-6-4-8(2)5-7-9/h4-7H,3H2,1-2H3

Upstream product

• 4755-77-5 Ethyl oxalyl chloride 
• 108-88-3 toluene 
• 95-92-1 oxalic acid diethyl ester 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 6957-89-7 Ethyl dichloro-(ethoxy)-acetate 
• 797756-83-3 3-hydroxy-2-(4-methylphenyl)acrylic acid ethyl ester 
• 14062-19-2 p-tolylacetic acid ethyl ester 
• 18584-23-1 hydroxy-p-tolyl-acetic acid ethyl ester 
• 1075-47-4 4-methylphenylglyoxal 
• 762-04-9 Diethyl phosphonate 
• 64-17-5 ethanol 
• 766-97-2 4-n-methylphenylacetylene 
• 62968-73-4 2-nitro-1-(p-tolyl)ethan-1-one 
• 7163-50-0 (4-methylphenyl)(oxo)acetic acid 

Downstream Products

• 93809-89-3 cyclohexyl-hydroxy-p-tolyl-acetic acid ethyl ester 
• 62281-66-7 Ester Ih 
• 79523-76-5 2,3-Di-p-tolyl-2,3-bis-triethylsilanyloxy-succinic acid diethyl ester 
• 114070-30-3 2-Hydroxy-3-methylene-2-p-tolyl-succinic acid 1-ethyl ester 4-methyl ester 
• 13474-74-3 3,3-dichloro-2-p-tolyl-acrylic acid ethyl ester 
• 916058-71-4 ethyl [N-(p-methoxyphenyl)imino]-(p-tolyl)acetate 
• 139016-20-9 (S)-1-(4-methylphenyl)-1,2-ethanediol 
• 179914-05-7 (R)-1-(4-methylphenyl)-1,2-ethanediol 
• 1013910-54-7 (R)-(-)-ethyl 2-hydroxy-3-nitro-2-p-tolylpropanoate 
• 1204769-80-1 4-benzyl 1-ethyl 2-hydroxy-2-(4-methylphenyl)butanedioate 
• 1033133-17-3 potassium oxo-(4-methylphenyl)acetate 
• 1233690-67-9 ethyl (4R,5S)-4-(4,4-dimethyl-2-oxooxazolidine-3-carbonyl)-2-thioxo-5-(p-tolyl)oxazolidine-5-carboxylate 

Relevant articles and documents

Electrochemical two-electron oxygen reduction reaction (ORR) induced aerobic oxidation of α-diazoesters

Electrochemical oxygen reduction reaction (ORR) is a powerful tool for introducing oxygen functional groups in synthetic chemistry. However, compared with the well-developed one-electron oxygen reduction process, the applications of two-electron oxygen re

Stereoselective Synthesis of Dihydrocoumarins via [1,2]-Phospha-Brook Rearrangement in Three-Component Coupling Reaction of α-Ketoesters, o-Quinone Methides, and Dialkyl Phosphites

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Metal-Free Oxidative Esterification of Ketones and Potassium Xanthates: Selective Synthesis of α-Ketoesters and Esters

A novel and efficient oxidative esterification for the selective synthesis of α-ketoesters and esters has been developed under metal-free conditions. In the protocol, various α-ketoesters and esters are available in high yields from commercially available ketones and potassium xanthates. Mechanistic studies have proven that potassium xanthate not only promotes oxidative esterification but also provides an alkoxy moiety for the reaction, which involves the cleavage and reconstruction of C-O bonds.