Technology Process of [1'-13C]-2',3',5'-tri-O-benzoyl-N4-benzoylcytidine
There total 7 articles about [1'-13C]-2',3',5'-tri-O-benzoyl-N4-benzoylcytidine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: (NH4)2SO4 / 14 h / Heating
2: 86 percent / TMSOTf / 1,2-dichloro-ethane / 5.5 h / 20 - 45 °C
With
ammonium sulfate; trimethylsilyl trifluoromethanesulfonate;
In
1,2-dichloro-ethane;
DOI:10.1016/S0008-6215(00)00327-X
- Guidance literature:
-
Multi-step reaction with 5 steps
1: H2SO4 / 0 °C
2: pyridine / 0 °C
3: 95 percent / BF3*Et2O / CH2Cl2 / 1 h / 0 °C
4: 95 percent / m-CPBA, NaHCO3 / CH2Cl2 / 1 h / 0 °C
5: 1) hexamethyldisilazane, 2) TMSOTf / 1) reflux, 2) 1,2-dichloroethane, r.t.
With
pyridine; trimethylsilyl trifluoromethanesulfonate; sulfuric acid; boron trifluoride diethyl etherate; sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; 1,1,1,3,3,3-hexamethyl-disilazane;
In
dichloromethane;
DOI:10.1016/S0040-4039(00)79089-7
- Guidance literature:
-
Multi-step reaction with 3 steps
1: BF3*Et2O / CH2Cl2
2: 95 percent / m-CPBA, NaHCO3 / CH2Cl2 / 1 h / 0 °C
3: 1) hexamethyldisilazane, 2) TMSOTf / 1) reflux, 2) 1,2-dichloroethane, r.t.
With
trimethylsilyl trifluoromethanesulfonate; boron trifluoride diethyl etherate; sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; 1,1,1,3,3,3-hexamethyl-disilazane;
In
dichloromethane;
DOI:10.1016/S0040-4039(00)79089-7
