Technology Process of 1-cyclohexyl-2-methylenecyclopropane
There total 5 articles about 1-cyclohexyl-2-methylenecyclopropane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: aq. NH4Cl / diethyl ether
2: Zn-Cu, I2, Et2O
With
diethyl ether; iodine; copper; ammonium chloride; zinc;
In
diethyl ether;
DOI:10.1021/jo00867a001
- Guidance literature:
-
With
potassium tert-butylate;
In
dimethyl sulfoxide;
at 20 ℃;
DOI:10.1021/ja9046894
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide / ethanol; water
2.1: n-butyllithium / tetrahydrofuran; hexane / -95 °C
2.2: -95 - 20 °C
3.1: potassium tert-butylate / dimethyl sulfoxide / 20 °C
With
n-butyllithium; potassium tert-butylate; N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide;
In
tetrahydrofuran; ethanol; hexane; water; dimethyl sulfoxide;
DOI:10.1021/ja9046894
