Toluene-4-sulfonic acid 2,2,2-trifluoro-1-(4-fluoro-phenyl)-ethyl ester

Base Information

Chemical Name:Toluene-4-sulfonic acid 2,2,2-trifluoro-1-(4-fluoro-phenyl)-ethyl ester
CAS No.:50562-20-4
Molecular Formula:C₁₅H₁₂F₄O₃S
Molecular Weight:348.318
Hs Code.:

Synonyms:Toluene-4-sulfonic acid 2,2,2-trifluoro-1-(4-fluoro-phenyl)-ethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Toluene-4-sulfonic acid 2,2,2-trifluoro-1-(4-fluoro-phenyl)-ethyl ester

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Technology Process of Toluene-4-sulfonic acid 2,2,2-trifluoro-1-(4-fluoro-phenyl)-ethyl ester

There total 1 articles about Toluene-4-sulfonic acid 2,2,2-trifluoro-1-(4-fluoro-phenyl)-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 17556-41-1,50562-19-1,131832-02-5
2,2,2-trifluoro-1-(4-fluorophenyl)ethanol

: 98-59-9
p-toluenesulfonyl chloride

: 50562-20-4
Toluene-4-sulfonic acid 2,2,2-trifluoro-1-(4-fluoro-phenyl)-ethyl ester

Guidance literature:: DOI:10.1021/jo00921a004

Reference yield: 33.0%

: 50562-20-4
Toluene-4-sulfonic acid 2,2,2-trifluoro-1-(4-fluoro-phenyl)-ethyl ester

: 81577-15-3
1-(1-Bromo-2,2,2-trifluoroethyl)-4-fluorobenzene

Guidance literature:: With potassium bromide; In diethylene glycol;

Reference yield:

: 50562-20-4
Toluene-4-sulfonic acid 2,2,2-trifluoro-1-(4-fluoro-phenyl)-ethyl ester

: 1256278-63-3
2,2-difluoro-1-(4-fluorophenyl)ethenyl p-toluenesulfonate

Guidance literature:: With lithium hexamethyldisilazane; In tetrahydrofuran; hexane; at -78 ℃; for 0.916667h; Inert atmosphere;
DOI:10.1002/adsc.202101388