5-{2-[3-(4-fluorophenyl)-isoxazol-5-yl]-2-[(E)-propoxyimino]-ethoxy}-isophthalic acid monomethyl ester

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Chemical Name:5-{2-[3-(4-fluorophenyl)-isoxazol-5-yl]-2-[(E)-propoxyimino]-ethoxy}-isophthalic acid monomethyl ester
CAS No.:937079-52-2
Molecular Formula:C₂₃H₂₁FN₂O₇
Molecular Weight:456.427
Hs Code.:

Synonyms:5-{2-[3-(4-fluorophenyl)-isoxazol-5-yl]-2-[(E)-propoxyimino]-ethoxy}-isophthalic acid monomethyl ester

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Chemical Property of 5-{2-[3-(4-fluorophenyl)-isoxazol-5-yl]-2-[(E)-propoxyimino]-ethoxy}-isophthalic acid monomethyl ester

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Technology Process of 5-{2-[3-(4-fluorophenyl)-isoxazol-5-yl]-2-[(E)-propoxyimino]-ethoxy}-isophthalic acid monomethyl ester

There total 1 articles about 5-{2-[3-(4-fluorophenyl)-isoxazol-5-yl]-2-[(E)-propoxyimino]-ethoxy}-isophthalic acid monomethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1174524-62-9
5-{2-[3-(4-fluorophenyl)-isoxazol-5-yl]-2-[(E)-propoxyimino]-ethoxy}-isophthalic acid dimethyl ester

: 937079-52-2
5-{2-[3-(4-fluorophenyl)-isoxazol-5-yl]-2-[(E)-propoxyimino]-ethoxy}-isophthalic acid monomethyl ester

Guidance literature:: 5-{2-[3-(4-fluorophenyl)-isoxazol-5-yl]-2-[(E)-propoxyimino]-ethoxy}-isophthalic acid dimethyl ester; With potassium hydroxide; In tetrahydrofuran; methanol; for 12h; Heating / reflux;

With hydrogenchloride; In tetrahydrofuran; methanol; water; pH=7;

Reference yield: 65.0%

: 937079-52-2
5-{2-[3-(4-fluorophenyl)-isoxazol-5-yl]-2-[(E)-propoxyimino]-ethoxy}-isophthalic acid monomethyl ester

: 765-30-0
Cyclopropylamine

: N-cyclopropyl-5-{2-[3-(4-fluorophenyl)-isoxazol-5-yl]-2-[(E)-propoxyimino]-ethoxy}-isophthalamic acid

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 12h;