1-Chlor-1-p-methoxy-phenyl-2-formyl-2-phenylaethylen

Base Information

• Chemical Name: 1-Chlor-1-p-methoxy-phenyl-2-formyl-2-phenylaethylen
• CAS No.: 42036-05-5
• Molecular Formula: C₁₆H₁₃ClO₂
• Molecular Weight: 272.731
• Mol file: 42036-05-5.mol

Synonyms:1-Chlor-1-p-methoxy-phenyl-2-formyl-2-phenylaethylen

Chemical Property of 1-Chlor-1-p-methoxy-phenyl-2-formyl-2-phenylaethylen

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Chlor-1-p-methoxy-phenyl-2-formyl-2-phenylaethylen

There total 6 articles about 1-Chlor-1-p-methoxy-phenyl-2-formyl-2-phenylaethylen which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(dimethylamino)-1-(4-methoxyphenyl)-2-phenyl-2-propen-1-one → 1-Chlor-1-p-methoxy-phenyl-2-formyl-2-phenylaethylen (42036-05-5)

Guidance literature:

With trichlorophosphate; In dichloromethane; at 20 ℃;

DOI:10.1016/j.tet.2018.04.017

Reference yield:

methoxybenzene (100-66-3) → 1-Chlor-1-p-methoxy-phenyl-2-formyl-2-phenylaethylen (42036-05-5)

Guidance literature:

Multi-step reaction with 3 steps

1: trifluoromethylsulfonic anhydride / dichloromethane / Cooling with ice

2: N,N-dimethyl-formamide / 2 h / 100 °C / Microwave irradiation

3: trichlorophosphate / dichloromethane / 20 °C

With trifluoromethylsulfonic anhydride; trichlorophosphate; In dichloromethane; N,N-dimethyl-formamide; 1: |Friedel-Crafts Acylation;

DOI:10.1016/j.tet.2018.04.017

Reference yield:

phenylacetic acid (103-82-2) → 1-Chlor-1-p-methoxy-phenyl-2-formyl-2-phenylaethylen (42036-05-5)

Guidance literature:

Multi-step reaction with 3 steps

1: trifluoromethylsulfonic anhydride / dichloromethane / Cooling with ice

2: N,N-dimethyl-formamide / 2 h / 100 °C / Microwave irradiation

3: trichlorophosphate / dichloromethane / 20 °C

With trifluoromethylsulfonic anhydride; trichlorophosphate; In dichloromethane; N,N-dimethyl-formamide; 1: |Friedel-Crafts Acylation;

DOI:10.1016/j.tet.2018.04.017

upstream raw materials:

methoxybenzene

phenylacetic acid

4-methoxyphenyl benzyl ketone

Downstream raw materials:

1-Mercapto-1-p-methoxyphenyl-2-formyl-2-phenylethylen

(Z)-1-(4-Methoxy-phenyl)-2-phenyl-3-phenylamino-propenethione