2-(4-Cyanophenyl)-3-hydroxypyridine

Base Information

• Chemical Name: 2-(4-Cyanophenyl)-3-hydroxypyridine
• CAS No.: 910649-33-1
• Molecular Formula: C₁₂H₈N₂O
• Molecular Weight: 196.208
• DSSTox Substance ID: DTXSID40682546
• Wikidata: Q82606966
• Mol file: 910649-33-1.mol

Synonyms:910649-33-1;2-(4-CYANOPHENYL)-3-HYDROXYPYRIDINE;4-(3-hydroxypyridin-2-yl)benzonitrile;SCHEMBL2142400;DTXSID40682546;MFCD18311953;AKOS006315843

Chemical Property of 2-(4-Cyanophenyl)-3-hydroxypyridine

Chemical Property:

• XLogP3: 1.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 196.063662883
• Heavy Atom Count: 15
• Complexity: 250

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=C(N=C1)C2=CC=C(C=C2)C#N)O

Technology Process of 2-(4-Cyanophenyl)-3-hydroxypyridine

There total 2 articles about 2-(4-Cyanophenyl)-3-hydroxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

→ 4-(3-hydroxypyridin-2-yl)benzonitrile (910649-33-1)

Guidance literature:

Reference yield: 54.0%

3-HYDROXYPYRIDINE (109-00-2) + 4-Aminobenzonitrile (873-74-5) → 4-(3-hydroxypyridin-2-yl)benzonitrile (910649-33-1)

Guidance literature:

4-Aminobenzonitrile; With hydrogenchloride; sodium nitrite; In water; at 0 ℃; for 0.5h;

3-HYDROXYPYRIDINE; With sulfuric acid; In water; at 20 ℃; for 20h; Inert atmosphere; Irradiation;

DOI:10.1002/chem.201703954

upstream raw materials:

3-HYDROXYPYRIDINE

4-Aminobenzonitrile