Technology Process of C14H18IN5O
There total 3 articles about C14H18IN5O which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Iodine monochloride;
In
methanol; N,N-dimethyl-formamide;
at 20 ℃;
Inert atmosphere;
Schlenk technique;
DOI:10.1021/jo301059u
- Guidance literature:
-
Multi-step reaction with 3 steps
1: water; toluene; tetrahydrofuran; hexane / Inert atmosphere; Schlenk technique; Reflux
2: hydrogenchloride; water / dichloromethane; ethanol; methanol / 12 h / 20 °C / Inert atmosphere; Schlenk technique
3: Iodine monochloride / methanol; N,N-dimethyl-formamide / 20 °C / Inert atmosphere; Schlenk technique
With
hydrogenchloride; water; Iodine monochloride;
In
tetrahydrofuran; methanol; ethanol; hexane; dichloromethane; water; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jo301059u
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: n-butyllithium / toluene; tetrahydrofuran; hexane / 2 h / -78 - 20 °C / Inert atmosphere; Schlenk technique
1.2: 18 h / -78 - 20 °C / Inert atmosphere; Schlenk technique
2.1: water; toluene; tetrahydrofuran; hexane / Inert atmosphere; Schlenk technique; Reflux
3.1: hydrogenchloride; water / dichloromethane; ethanol; methanol / 12 h / 20 °C / Inert atmosphere; Schlenk technique
4.1: Iodine monochloride / methanol; N,N-dimethyl-formamide / 20 °C / Inert atmosphere; Schlenk technique
With
hydrogenchloride; n-butyllithium; water; Iodine monochloride;
In
tetrahydrofuran; methanol; ethanol; hexane; dichloromethane; water; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jo301059u
