55359-65-4

Basic information

• Product Name: Benzene, 1-(methoxymethoxy)-2-methyl-
• Synonyms: 2-methoxymethoxytoluene;o-methyl methoxymethoxybenzene;1-methoxymethoxy-2-methylbenzene
• CAS NO: 55359-65-4
• Molecular Formula: C9H12O2
• Molecular Weight: 152.193
• Mol File: 55359-65-4.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(methoxymethoxy)-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(methoxymethoxy)-2-methyl-(55359-65-4)
• EPA Substance Registry System: Benzene, 1-(methoxymethoxy)-2-methyl-(55359-65-4)

Safety Data

• Hazardous Substances Data: 55359-65-4(Hazardous Substances Data)

Upstream product

• 109-87-5 Dimethoxymethane 
• 95-48-7 ortho-cresol 
• 824-91-9 O-methoxymethylphenol 
• 74-88-4 methyl iodide 
• 107-30-2 chloromethyl methyl ether 
• 13057-17-5 bromethyl methyl ether 
• 4549-72-8 sodium o-cresolate 

Downstream Products

• 95481-41-7 (2-Methoxymethoxy-3-methyl-phenyl)-carbamic acid tert-butyl ester 
• 55359-67-6 2-(Methoxymethoxy)-3-methylbenzaldehyde 
• 95510-87-5 (2-Methoxy-3-methyl-phenyl)-carbamic acid tert-butyl ester 
• 95510-88-6 2-tert-Butoxycarbonylamino-3-methoxy-4-methyl-benzoic acid 
• 1352038-40-4 C₉⁽¹³⁾CH₁₂O₃ 
• 1352038-42-6 C₇⁽¹³⁾CH₈O₂ 
• 1352038-48-2 C₉⁽¹³⁾CH₁₂O₄P^(1-)*C₁₆H₃₆N⁽¹⁺⁾ 
• 1202677-37-9 2-methyl-6-(pyridin-4-yl)phenol 
• 259209-22-8 2-hydroxy-3-methylphenyl boronic acid 
• 496955-32-9 ethyl-(2-methoxymethoxyphenyl)acetate 
• 553-86-6 benzofuran-2(3H)-one 
• 614-75-5 2-Hydroxyphenylacetic acid 
• 120743-97-7 <(o-hydroxyphenyl)methyl>dimethylphenylsilane 
• 1344713-92-3 (2-formylphenyl)-6-methyl trifluoromethanesulfonate 

Relevant articles and documents

Synthetic method of benzofuranone

The invention provides a synthetic method of benzofuranone. According to the method, o-cresol which is relatively easy to obtain is used as an initial raw material, and the target product benzofuranone is prepared through four-step reaction; and the whole preparation process is mild in condition, high in yield, easy to operate, small in environmental pollution and suitable for large-scale industrial production.

4,5-Dimethyl-2-Iodoxybenzenesulfonic Acid Catalyzed Site-Selective Oxidation of 2-Substituted Phenols to 1,2-Quinols

A site-selective hydroxylative dearomatization of 2-substituted phenols to either 1,2-benzoquinols or their cyclodimers, catalyzed by 4,5-dimethyl-2-iodoxybenzenesulfonic acid with Oxone, has been developed. Natural products such as biscarvacrol and lacinilene C methyl ether could be synthesized efficiently under mild reaction conditions. Furthermore, both the reaction rate and site selectivity could be further improved by the introduction of a trialkylsilylmethyl substituent at the 2-position of phenols. The corresponding 1,2-quinols could be transformed into various useful structural motifs by [4+2] cycloaddition cascade reactions.

Enantioselective synthesis of multisubstituted biaryl skeleton by chiral phosphoric acid catalyzed desymmetrization/kinetic resolution sequence

Described herein is the enantioselective synthesis of multisubstituted biaryl derivatives by chiral phosphoric acid catalyzed asymmetric bromination. Two asymmetric reactions (desymmetrization and kinetic resolution) proceeded successively to afford chiral biaryls in excellent enantioselectivities (up to 99% ee). Both experimental and computational studies suggested that this excellent selectivity could be achieved via a highly organized hydrogen bond network among a substrate, a catalyst (chiral phosphoric acid), and a brominating reagent (N-bromophthalimide).