1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Base Information

Chemical Name:1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE
CAS No.:74389-68-7
Molecular Formula:C₂₆H₅₄NO₇P
Molecular Weight:523.691
Hs Code.:
UNII:42EWD89I80
DSSTox Substance ID:DTXSID00225377
Wikipedia:Platelet-activating_factor
Wikidata:Q420577
NCI Thesaurus Code:C16998
Pharos Ligand ID:NM8NKPBMTKJM
Metabolomics Workbench ID:14671
ChEMBL ID:CHEMBL1235246
Mol file:74389-68-7.mol

Synonyms:3,5,9-Trioxa-4-phosphapentacosan-1-aminium,7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-, inner salt, 4-oxide, (R)-;1-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine;1-O-Hexadecyl-2-O-acetyl-sn-glycero-3-phosphocholine;1-O-Hexadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine;1-O-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine;1-O-Hexadecyl-2-acetyl-sn-glycerophosphocholine;1-O-Hexadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine;1-O-Hexadecyl-platelet-activating factor; Blood platelet-activating factor;Blood platelet-activating factor acether; C16-PAF; C16-PAF acether; PAF; PAF16; PAF acether; Platelet-activating factor; Platelet-activating factor acether

Suppliers and Price of 1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
PAF(C16)
5mg
$ 140.00

Tocris
PAF(C16)
1
$ 71.00

Sigma-Aldrich
β-Acetyl-γ-O-hexadecyl-L-α-phosphatidylcholine hydrate ≥98%
5mg
$ 120.00

Sigma-Aldrich
β-Acetyl-γ-O-hexadecyl-L-α-phosphatidylcholine hydrate ≥98%
1mg
$ 48.80

Sigma-Aldrich
Platelet Activating Factor-16
1mg
$ 42.36

Sigma-Aldrich
β-Acetyl-γ-O-hexadecyl-L-α-phosphatidylcholine hydrate ≥98%
10mg
$ 287.00

Sigma-Aldrich
Platelet Activating Factor-16
5mg
$ 97.12

Sigma-Aldrich
β-Acetyl-γ-O-hexadecyl-L-α-phosphatidylcholine hydrate ≥98%
25mg
$ 560.00

CSNpharm
PAF(C16)
100mg
$ 703.00

Crysdot
PAF(C16) 95+%
100mg
$ 703.00

Total 8 raw suppliers

Chemical Property of 1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Chemical Property:

Melting Point:247 °C
PSA：103.93000
LogP:6.69400
Storage Temp.:−20°C
Solubility.:Soluble in H2O or ethanol
XLogP3:6.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:26
Exact Mass:523.36379006
Heavy Atom Count:35
Complexity:546

Purity/Quality:

97% ^*data from raw suppliers

PAF(C16) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22-38-40-48/20/22
Safety Statements: 36/37-24/25-22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCCCCCCCCCCCOCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)C
Isomeric SMILES:CCCCCCCCCCCCCCCCOC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)C
Uses PAF (C16) (cas# 74389-68-7) is a blood platelet-activating factor, used to study human airway smooth muscle cell line. C16-02:0 PC or 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine may be used as a substrate in enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay. It may also be used to study its physicochemical properties and its interaction with peptides derived from the C-terminal domains of human apolipoprotein E.

Technology Process of 1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE

There total 47 articles about 1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%