Methyl 2-(3,4-dimethoxyphenyl)propanoate

Base Information

Chemical Name:Methyl 2-(3,4-dimethoxyphenyl)propanoate
CAS No.:29207-02-1
Molecular Formula:C₁₂H₁₆O₄
Molecular Weight:224.257
Hs Code.:
DSSTox Substance ID:DTXSID201264011

Synonyms:methyl 2-(3,4-dimethoxyphenyl)propanoate;29207-02-1;SCHEMBL5022505;DUMQFLGJMUWUPV-UHFFFAOYSA-N;DTXSID201264011;AKOS011682691;WS-00664;D86227;Methyl 3,4-dimethoxy-alpha-methylbenzeneacetate

Suppliers and Price of Methyl 2-(3,4-dimethoxyphenyl)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Methyl 2-(3,4-dimethoxyphenyl)propanoate

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:224.10485899
Heavy Atom Count:16
Complexity:229

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C1=CC(=C(C=C1)OC)OC)C(=O)OC

Technology Process of Methyl 2-(3,4-dimethoxyphenyl)propanoate

There total 3 articles about Methyl 2-(3,4-dimethoxyphenyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 15964-79-1
methyl (3,4-dimethoxyphenyl)acetate

: 74-88-4
methyl iodide

: 29207-02-1
methyl 2-(3,4-dimethoxyphenyl)propanoate

Guidance literature:: methyl (3,4-dimethoxyphenyl)acetate; With n-butyllithium; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 1.25h;

methyl iodide; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

Reference yield:

: 93-40-3
(3,4-Dimethoxyphenyl)acetic acid

: 29207-02-1
methyl 2-(3,4-dimethoxyphenyl)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide / 0.5 h / 0 - 20 °C

1.2: 0.17 h

2.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C

2.2: 1 h / -78 °C

With oxalyl dichloride; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm301488q