Tert-butyl 4-({5-methyl-4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-2-yl}sulfanyl)butanoate

Base Information

Chemical Name:Tert-butyl 4-({5-methyl-4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-2-yl}sulfanyl)butanoate
CAS No.:1236765-34-6
Molecular Formula:C₂₃H₂₆F₃N₃O₄S
Molecular Weight:497.538
Hs Code.:

Synonyms:Tert-butyl 4-({5-methyl-4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-2-yl}sulfanyl)butanoate

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Chemical Property of Tert-butyl 4-({5-methyl-4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-2-yl}sulfanyl)butanoate

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Technology Process of Tert-butyl 4-({5-methyl-4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-2-yl}sulfanyl)butanoate

There total 1 articles about Tert-butyl 4-({5-methyl-4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-2-yl}sulfanyl)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1236765-33-5
tert-butyl 4-({4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-2-yl}sulfanyl)butanoate

: 74-88-4
methyl iodide

: 1236765-34-6
Tert-butyl 4-({5-methyl-4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-2-yl}sulfanyl)butanoate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 40 ℃; for 6h;

Reference yield:

: 151-18-8,60585-38-8
2-cyanoethylamine

: 1236765-34-6
Tert-butyl 4-({5-methyl-4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-2-yl}sulfanyl)butanoate

: 1236765-35-7
N-(2-cyanoethyl)-4-({5-methyl-4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-2-yl}sulfanyl)butanamide

Guidance literature:: Tert-butyl 4-({5-methyl-4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-2-yl}sulfanyl)butanoate; With hydrogenchloride; water; In acetonitrile; for 0.5h; Reflux;

2-cyanoethylamine; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 12h;