3'-azido-2',3'-dideoxy-5-methylcytidine

Base Information

Chemical Name:3'-azido-2',3'-dideoxy-5-methylcytidine
CAS No.:87190-79-2
Molecular Formula:C₁₀H₁₄N₆O₃
Molecular Weight:266.26
Hs Code.:
Mol file:87190-79-2.mol

Synonyms:CS-92;AZMC;3'-Azido-2',3'-dideoxy-5-methylcytidine;Az-Dcme;Azddmec;AZ-5MeC;

Suppliers and Price of 3'-azido-2',3'-dideoxy-5-methylcytidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 10 raw suppliers

Chemical Property of 3'-azido-2',3'-dideoxy-5-methylcytidine

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：141.11000
Density:g/cm³
LogP:-0.11224

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses AzddMeC is used as an antiviral agent for treating viral infection.

Technology Process of 3'-azido-2',3'-dideoxy-5-methylcytidine

There total 5 articles about 3'-azido-2',3'-dideoxy-5-methylcytidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 87190-77-0
1-(5-O-Acetyl-3-azido-2,3-dideoxy-β-D-erythro-pentofuranosyl)-5-methyl-4-(1,2,4-triazol-1-yl)-2(1H)-pyrimidinone

: 87190-79-2
3'-azido-5-methyl-2',3'-dideoxycytidine

Guidance literature:: With ammonium hydroxide; In 1,4-dioxane; for 4h; Ambient temperature;
DOI:10.1021/jm00366a006

Reference yield:

: 4-Amino-1-((2R,4S,5S)-4-azido-5-trityloxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidin-2-one

: 87190-79-2
3'-azido-5-methyl-2',3'-dideoxycytidine

Guidance literature:: With acetic acid; at 100 ℃; for 0.333333h; Yield given;
DOI:10.1021/jm00391a003

Reference yield:

: 1-((2R,4S,5S)-4-Azido-5-trityloxymethyl-tetrahydro-furan-2-yl)-4-chloro-5-methyl-1H-pyrimidin-2-one

: 87190-79-2
3'-azido-5-methyl-2',3'-dideoxycytidine

Guidance literature:: Multi-step reaction with 2 steps

1: 33percent aq. NH₃ / acetonitrile; pyridine / 2 h / Ambient temperature

2: 80percent aq. CH₃COOH / 0.33 h / 100 °C

With ammonium hydroxide; acetic acid; In pyridine; acetonitrile;
DOI:10.1021/jm00391a003