2,2,6,6-tetraethyl-1-[1-(4-iodomethylphenyl)ethoxy]-4-methoxypiperidine

Base Information

Chemical Name:2,2,6,6-tetraethyl-1-[1-(4-iodomethylphenyl)ethoxy]-4-methoxypiperidine
CAS No.:1003593-04-1
Molecular Formula:C₂₃H₃₈INO₂
Molecular Weight:487.465
Hs Code.:

Synonyms:2,2,6,6-tetraethyl-1-[1-(4-iodomethylphenyl)ethoxy]-4-methoxypiperidine

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Chemical Property of 2,2,6,6-tetraethyl-1-[1-(4-iodomethylphenyl)ethoxy]-4-methoxypiperidine

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Technology Process of 2,2,6,6-tetraethyl-1-[1-(4-iodomethylphenyl)ethoxy]-4-methoxypiperidine

There total 1 articles about 2,2,6,6-tetraethyl-1-[1-(4-iodomethylphenyl)ethoxy]-4-methoxypiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1003593-30-3
{4-[1-(2,2,6,6-tetraethyl-4-methoxypiperidin-1-yloxy)ethyl]phenyl}methanol

: 1003593-04-1
2,2,6,6-tetraethyl-1-[1-(4-iodomethylphenyl)ethoxy]-4-methoxypiperidine

Guidance literature:: With chloro-trimethyl-silane; sodium iodide; In acetonitrile; at 20 ℃; for 2h;
DOI:10.1039/b713083j

Reference yield: 51.0%

: 1003593-04-1
2,2,6,6-tetraethyl-1-[1-(4-iodomethylphenyl)ethoxy]-4-methoxypiperidine

: 3262-72-4
(S)-N-(tert-butoxycarbonyl)serine

: 1003593-08-5
(S)-2-tert-butoxycarbonylamino-3-{4-[1-(2,2,6,6-tetraethyl-4-methoxypiperidin-1-yloxy)ethyl]benzyloxy}propionic acid

Guidance literature:: (S)-N-(tert-butoxycarbonyl)serine; With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 1h;

2,2,6,6-tetraethyl-1-[1-(4-iodomethylphenyl)ethoxy]-4-methoxypiperidine; In N,N-dimethyl-formamide; at 20 ℃; for 3h; Further stages.;
DOI:10.1039/b713083j