N-{[2-(4-amidino-2-fluorophenoxycarbonyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-6-yl]carbonyl}-L-aspartic acid trifluoroacetate

Base Information

Chemical Name:N-{[2-(4-amidino-2-fluorophenoxycarbonyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-6-yl]carbonyl}-L-aspartic acid trifluoroacetate
CAS No.:1415762-96-7
Molecular Formula:C₂HF₃O₂*C₂₀H₁₉FN₄O₇S
Molecular Weight:592.482
Hs Code.:

Synonyms:N-{[2-(4-amidino-2-fluorophenoxycarbonyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-6-yl]carbonyl}-L-aspartic acid trifluoroacetate

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Chemical Property of N-{[2-(4-amidino-2-fluorophenoxycarbonyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-6-yl]carbonyl}-L-aspartic acid trifluoroacetate

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Technology Process of N-{[2-(4-amidino-2-fluorophenoxycarbonyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-6-yl]carbonyl}-L-aspartic acid trifluoroacetate

There total 2 articles about N-{[2-(4-amidino-2-fluorophenoxycarbonyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-6-yl]carbonyl}-L-aspartic acid trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1311290-63-7
4-amidino-2-fluorophenol trifluoroacetate

: N-(1H-imidazol-1-ylcarbonyl)-L-aspartic acid di-tert-butyl ester

: 1892-57-5,754131-18-5
N-(3-dimethylaminopropyl)-N-ethylcarbodiimide

: 165947-51-3
6-(tert-butoxycarbonyl)-4,5,6,7-tetrahydrothieno [2,3-c]pyridine-2-carboxylic acid

: 1415762-96-7
N-{[2-(4-amidino-2-fluorophenoxycarbonyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-6-yl]carbonyl}-L-aspartic acid trifluoroacetate

Guidance literature:: With pyridine; hydrogenchloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; acetonitrile; trifluoroacetic acid;

Reference yield:

: 405-04-9
3-fluoro-4-hydroxybenzonitrile

: 1415762-96-7
N-{[2-(4-amidino-2-fluorophenoxycarbonyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-6-yl]carbonyl}-L-aspartic acid trifluoroacetate

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride; ammonium carbonate; trifluoroacetic acid / ethanol; 1,4-dioxane

2: N-ethyl-N,N-diisopropylamine; pyridine; hydrogenchloride / acetonitrile; dichloromethane; trifluoroacetic acid

With pyridine; ammonium carbonate; hydrogenchloride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In 1,4-dioxane; ethanol; dichloromethane; acetonitrile; trifluoroacetic acid;