endo-2-hydroxybicyclo<2.1.0>pentane

Base Information

• Chemical Name: endo-2-hydroxybicyclo<2.1.0>pentane
• CAS No.: 149404-85-3
• Molecular Formula: C₅H₈O
• Molecular Weight: 84.1179
• Mol file: 149404-85-3.mol

Synonyms:endo-2-hydroxybicyclo<2.1.0>pentane

Chemical Property of endo-2-hydroxybicyclo<2.1.0>pentane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of endo-2-hydroxybicyclo<2.1.0>pentane

There total 3 articles about endo-2-hydroxybicyclo<2.1.0>pentane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bicyclo[2.1.0]pentane (185-94-4) → cyclopent-3-enol (14320-38-8) + endo-2-hydroxybicyclo<2.1.0>pentane (149404-85-3)

Guidance literature:

microsomal cytochrome P-450;

DOI:10.1021/ja00245a037

Reference yield:

bicyclo[2.1.0]pentane (185-94-4) → cyclopent-2-enone (930-30-3) + cyclopent-3-enol (14320-38-8) + 3-Cyclopentenon (14320-37-7) + endo-bicyclo<2.1.0>pentan-2-ol (24461-57-2,24461-58-3,149404-85-3)

Guidance literature:

With DL-dithiothreitol; Pseudomonas putida GPo₁ alkane hydroxylase; β-nicotinamide adenine dinucleotide?reduced; In glycerol; pH=7.4; Kinetics; aq. phosphate buffer;

DOI:10.1002/anie.200801184

Reference yield:

bicyclo[2.1.0]pentane (185-94-4) → endo-bicyclo<2.1.0>pentan-2-ol (24461-57-2,24461-58-3,149404-85-3) + (1S,2S,4R)-Bicyclo[2.1.0]pentane-2,3-diol

Guidance literature:

With 3,3-dimethyldioxirane; In acetone; at 20 ℃; for 2.5h; Further Variations:; Reagents; Solvents; Temperatures; Product distribution;

DOI:10.1016/S0040-4039(01)01434-4

upstream raw materials:

bicyclo[2.1.0]pentane

Refernces

• 1、 Austin, Rachel N.,Luddy, Kate,Erickson, Karla,Pender-Cudlip, Marilla,Bertrand, Erin,Deng, Dayi,Buzdygon, Ryan S.,Van Beilen, Jan B.,Groves, John T.. "Cage escape competes with geminate recombination during alkane hydroxylation by the diiron oxygenase AlkB". supporting information; experimental part. p. 5232 - 5234. Retrieved 2009/04/04.