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Bicyclo[2,1,0]pentane, also known as spiropentane, is a unique chemical compound characterized by its bicyclic ring structure, consisting of two connected cyclopropane rings. It is a colorless, flammable liquid at room temperature and is recognized for its highly strained hydrocarbon nature due to the close proximity of the carbon atoms in the cyclopropane rings. This molecular strain makes Bicyclo[2,1,0]pentane an intriguing subject for research in organic chemistry, particularly in understanding the effects of ring strain in organic molecules.

185-94-4

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185-94-4 Usage

Uses

Used in Organic Chemistry Synthesis:
Bicyclo[2,1,0]pentane is utilized as a building block in various organic chemistry syntheses for its ability to undergo a range of chemical reactions, such as ring-opening reactions and cycloadditions. Its highly strained structure allows for the creation of novel compounds and contributes to the advancement of organic synthesis techniques.
Used in Research and Education:
In the field of research and education, Bicyclo[2,1,0]pentane serves as an important molecule for studying the effects of ring strain in organic chemistry. Its unique properties and reactivity provide valuable insights into the behavior of strained organic molecules, aiding in the development of new theories and understanding of molecular structure and dynamics.
Used in Material Science:
Bicyclo[2,1,0]pentane's strained structure and reactivity also make it a candidate for material science applications, where its properties can be harnessed to develop new materials with specific characteristics. For instance, its ring-opening reactions could be exploited in the synthesis of polymers or other materials with tailored properties.
Used in Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, the unique reactivity and strained nature of Bicyclo[2,1,0]pentane could potentially be applied in the pharmaceutical industry for the development of novel drug molecules. Its ability to undergo various chemical reactions may facilitate the synthesis of complex organic compounds with potential medicinal properties.

Check Digit Verification of cas no

The CAS Registry Mumber 185-94-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,8 and 5 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 185-94:
(5*1)+(4*8)+(3*5)+(2*9)+(1*4)=74
74 % 10 = 4
So 185-94-4 is a valid CAS Registry Number.
InChI:InChI=1/C5H8/c1-2-5-3-4(1)5/h4-5H,1-3H2

185-94-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name housane

1.2 Other means of identification

Product number -
Other names Bicyclo-<2.1.0>pentan

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:185-94-4 SDS

185-94-4Relevant academic research and scientific papers

Photodissociation of a bicyclic azoalkane: Time-resolved coherent anti-stokes Raman spectroscopy studies of vapor-phase 2,3-diazabicyclo[2.2.1]hept-2-ene

Adams, J. Stephen,Weisman, R. Bruce,Engel, Paul S.

, p. 9115 - 9121 (1990)

The photodissociative mechanism of vapor-phase 2,3-diazabicyclo[2.2.1]hept-2-ene (DBH) has been studied with nanosecond-regime transient spectroscopic methods. Following excitation of the vibrationless S1 level at 338.5 nm, data from time-resolved CARS (a vibrational spectroscopy) show the appearance rate for formation of N2 to be 4 × 107 s-1. This value is significantly slower than the 5 × 108 s-1 principal component observed in S1 fluorescence decay, establishing that the dissociating state is not S1. CARS measurements on the nascent N2 photofragments reveal a vibrational distribution (84% v = 0, 12% v = 1) very similar to that observed earlier for the nitrogen formed in the stepwise photodissociation of azomethane. This result and the low level of nascent rotational excitation suggest that dissociation into N2 plus 1,3-cyclopentanediyl biradical occurs from an excited state of the diazenyl biradical that has a linear CNN bond angle. Transient CARS probing has also revealed the subsequent appearance of bicyclo[2.1.0]pentane formed by ring closure of the 1,3-cyclopentanediyl biradicals. Formation kinetics of this ring closure product shows a single first-order component with a rate coefficient of approximately 5.1 × 106 s-1. This observation implies that S1 excitation of vapor-phase DBH produces 1,3-cyclopentanediyl biradicals only in their ground triplet state. Mechanistic differences between the gas-phase photochemistries of DBH and acyclic azoalkanes are attributed to a low-lying excited state of the diazenyl biradical that becomes accessible in DBH through the release of ring strain energy.

UV Laser Photochemistry: Triplet Biradical Trapping Efficiencies and Lifetimes

Adam, Waldemar,Hannemann, Klaus,Wilson, R. Marshall

, p. 929 - 935 (1986)

The trapping of triplet 1,3-cyclopentadiyl (1a) and the triplet 1,4-biradical 2-cyclopent-2-enyl (6) with molecular oxygen has been studied quantitatively.The lifetime of 1a has been found to range between 720 and 900 ns and that of 6 between 53 and 94 ns depending on the solvent.The biradical 1a was found to be trapped in essentially quantitative yield with no indication of oxygen-catalyzed intersystem crossing.In contrast, 6 was found to be trapped in 54-79percent yield with the residual biradical quenching being due to oxygen-catalyzed intersystem crossing.These and other biradical trapping data have been correlated with 1,3-biradical geometries and found to be in accord with Salem's rules for spin-orbit coupling in triplet biradicals.

Time-resolved infrared studies of triplet 1,3-cyclopentanediyl

Showalter, Brett M.,Bentz, Timothy C.,Ryzhkov, Lev R.,Hadad, Christopher M.,Toscano, John P.

, p. 309 - 312 (2000)

Triplet-sensitized photolysis of 2,3-diazabicyclo[2.2.1]hept-2-ene (1) in argon- or oxygen- saturated acetonitrile-d3 solutions results in the formation of bicyclo[2.1.0]pentane (3), a ring closure product arising from an intermediate 1,3-cyclopentanediyl triplet biradical (2). Time-resolved infrared (TRIR) spectroscopy was used to monitor the kinetics of bicyclopentane 3 production. This analysis provides a measurement of the triplet biradical lifetime and an estimate of the bimolecular reaction rate between biradical 2 and oxygen, both in good agreement with previous investigations. Our studies also indicate that certain IR bands due to 3 in the C-H stretching region overlap with corresponding bands in biradical 2. This interpretation is supported by computational investigations. Copyright

Photochemistry of the Azoalkanes 2,3-Diazabicyclohept-2-ene and Spirodiazabicyclohept-2-ene>: On the Questions of One-Bond vs. Two-Bond Cleavage during the Denitrogenation, Cyclization vs. Rearrangement of the 1,3-Diradicals, and Double Inversion.

Adam, Waldemar,Oppenlaender, Thomas,Zang, Gerald

, p. 3303 - 3312 (1985)

The thermolysis and 350-nm and 185-nm photolyses of the azoalkanes 2,3-diazabicyclohept-2-ene (1a) and spirodiazabicyclohept-2-ene> (1b) have been investigated.The exo/endo stereochemistry in the bicyclopentanes 2a,b and in the rearranged olefin 3b was determined by deuteration experiments using 5,6-exo-dideuterioazoalkanes 1a,b-d2.Whereas thermal and direct photochemical (350 nm; n, ?*) denitrogenation of azoalkane 1a-d2 led exclusively (>99percent) to bicyclopentane 2a-d2 with preferential (1.54,2.94) double inversion, the triplet-sensitized photolysis afforded nearly complete stereoequlibration.In 185-nm denitrogenetion an unexpectedly high exo/endo ratio (3.1) for bicyclopentane 2a-d2 was found, besides isomerization to cyclopentene 2a-d2.Similar results were obtained in the denitrogenation of spiroazoalkane 1b-d2, which exhibited exo stereochemical preferences in both photoproducts spiropentane-5,1'-cyclopropane> 2b-d2 and bicyclohept-1-ene 3b-d2.The 350-nm photolysis of azoalkane 1b-d2 gave preferential formation of exo-spirobicyclopentane 2b-d2 and exo-olefin 3b-d2 whereas triplet-sensitized decomposition yielded almost complete loss of stereochemical preference in the olefin 3b-d2.The 185-nm photolysis of azoalkane 1b-d2 showed similar behavior compared with the azoalkane 1a, eg., at high exo/endo ratio in spirobicyclopentane 2b-d2.Also olefin 3b was formed with complete stereoequilibration.These diverse experimental results are discussed in terms of one-bond vs. two-bond cleavage processes leading to the diazenyl diradicals D'?,? and D'?,? in the case of low-energy activation (350-nm photolysis and thermolysis) and 1,3-cyclopentadiyls D?,? and D?,? on high-energy activation (185-nm activation).The relatively high degree of double inversion in the corresponding bicyclopentanes and the formation of rearranged cycloalkenes in the 185-nm photodenitrogenation is presumably a direct consequence of concerted two-bond cleavage via the formation of 1D?,? and zwitterionic states of the 1,3-diradical.A Salem diagram for one-bond and two-bond denitrogenation was most helpful in rationalizing these results mechanistically.

Determination of the Enthalpy and Reaction Volume Changes of Organic Photoreactions Using Photoacoustic Calorimetry

Herman, Michael S.,Goodman, Joshua L.

, p. 1849 - 1854 (1989)

Photoacoustic calorimetry (PAC) can be used to measure both the thermal and reaction volume changes for photoinitiated reactions.The photoreactions of 2,3-diazabicyclohept-2-ene (DBH), diphenylcyclopropenone (DPC), and trans-stilbene (TS) are investigated by PAC.The resolution of these experimental volume changes is accomplished by either a temperature dependence or a binary solvent mixture method.The thermal volume changes yield the enthalpies of reaction in solution, which can be compared to literature values.In two cases (DPH and DPC), the values are moreendothermic than those predicted from gas-phase heats of formation.The differences can possibly be attributed to differential solvation of the reactants and products in the polar solvents employed.Absolute reaction volume changes for the photoreactions are also obtained for the photoreactions.PAC is a useful alternative technique to pressure-dependence studies to obtain this information.These volume changes can further be time-resolved to provide kinetic information about the photoprocesses.

Dynamics of the Thermal Decomposition of 2,3-Diazabicyclo[2.2.1]hept-2-ene

Simpson,Wilson,Adam

, p. 4728 - 4732 (1991)

The dynamics of the thermal decomposition of 2,3-diazabicyclo[2.2.1]hept-2-ene (DBH) have been investigated over the temperature range 900-1400 K. A tunable continuous wave CO laser was used to follow the vibrational energy content of the coupled CO-N2 system from the initial to the equilibrium conditions. It has been shown that the N2 is born with very little vibrational energy, while the bicyclo[2.1.0]pentane is born with an excess over the equilibrium distribution. These results provide clear evidence against the concerted decomposition mechanism.

Viscosity dependence of the denitrogenation quantum yield in azoalkane photolysis: Experimental evidence for reversible formation of the diazenyl diradical

Adam, Waldemar,Corley, David A.,Trofimov, Alexei V.,White, Rick C.

, p. 4277 - 4280 (2002)

(equation presented) Experimental evidence is reported for the reversible formation of the singlet diazenyl diradical (1DZ), photolytically generated from the structurally elaborate DBH-type azoalkane. Reversiblity of the 1DZ formation manifests itself through the decrease of the photodenitrogenation quantum yield over a ca. 40-fold viscosity variation (from 0.5 to 19.3 cP). This viscosity behavior is interpreted in terms of frictional effects on the competitive reaction modes of the diazenyl diradical.

Transition-metal-promoted chemoselective photoreactions at the cucurbituril rim

Koner, Apurba L.,Marquez, Cesar,Dickman, Michael H.,Nau, Werner M.

supporting information; experimental part, p. 545 - 548 (2011/03/16)

When included in a supramolecular barrel with transition-metal ions as lids, bicyclic azoalkanes undergo phase-selective photolysis to afford new photoproducts and photoproduct distributions. In the presence of the macrocycle cucurbit[7]uril and Ag+ ions, 2,3-diazabicyclo[2.2.1]hept-2-ene forms a ternary host-guest inclusion complex in which the cations are coordinated to the carbonyl rims of the host. Direct photolysis of this ternary complex provides cyclopentene as a new photoproduct.

On the Mechanism of the Benzophenone-Sensitized Photolysis of 2,3-Diazabicyclohept-2-ene in the Laser Jet: Evidence for Intermolecular Triplet Diradical Reactions

Adam, Waldemar,Finzel, Ralf,Walther, Barbara

, p. 2137 - 2142 (2007/10/02)

The benzophenone-sensitized laser jet photolysis of 2,3-diazabicyclohept-2-ene (1) affords, besides the previously reported cyclopentene and housane (2), also cyclopentane, cyclopentadiene, and the dimers bicyclopent-2-en-1-yl (7), 3-cyclopentylcyclopent-1-ene (8), and 1,1'-bicyclopentyl (9).As a model reaction, the pyrolysis of dimer 8 at 600 deg C/ 20 Torr leads to the other dimers 7 and 9 together with cyclopentadiene, cyclopentene, and traces of cyclopentane.Control experiments showed that H abstraction by the cyclopentane-1,3-diyl diradical (3) from cyclohexene (as model substrate for cyclopentene) and addition to housane (2) with formation of diradical 6 are unlikely pathways.Instead, the product data available can be best explained in terms of an intermolecular disproportionation of two diradicals 3 to give the cyclopent-2-en-1-yl (4) and cyclopentyl (5) radical pair, which is subsequently converted to the observed products by in-cage and out-of-cage coupling and H transfer reactions.Such intermolecular diradical chemistry becomes feasible due to the high steady-state concentrations (ca. micromolar) generated in the laser jet.Two-photon processes take place, but are of subordinate importance. - Key Words: Laser jet/ Azoalkane/ Diradical/ Radical coupling

Preparation of Bicycloalkanes by Electrochemical Reduction of 1,3-Dibromocycloalkanes

Hoffmann, Joachim,Voss, Juergen

, p. 1415 - 1420 (2007/10/02)

Good yields of bicyclo pentane (17) and bicyclo-hexane(3) are obtained on electroreduction of the corresponding 1,3-dibromocycloalkanes.The results do not depend upon the stereochemistry of the starting material (14 vs. 15 or 11 vs. 12).Key Words: Electrochemical reduction / Bicycloalkanes / Cycloalkanes, 1,3-dibromo / Hunsdiecker reaction / 1,3-Cycloalkanedicarboxylic acids

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