5-acetoxyhexyl phenyl sulfide

Base Information

• Chemical Name: 5-acetoxyhexyl phenyl sulfide
• CAS No.: 77657-99-9
• Molecular Formula: C₁₄H₂₀O₂S
• Molecular Weight: 252.378
• Mol file: 77657-99-9.mol

Synonyms:5-acetoxyhexyl phenyl sulfide

Chemical Property of 5-acetoxyhexyl phenyl sulfide

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 5-acetoxyhexyl phenyl sulfide

There total 1 articles about 5-acetoxyhexyl phenyl sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

sodium thiophenolate (930-69-8) + 5-acetoxy-1-bromohexane (344325-55-9) → 5-acetoxyhexyl phenyl sulfide (77657-99-9)

Guidance literature:

DOI:10.1246/bcsj.53.3615

Reference yield: 95.0%

5-acetoxyhexyl phenyl sulfide (77657-99-9) → 6-phenylthio-2-hexanol (77657-89-7)

Guidance literature:

With potassium hydroxide; In 1,4-dioxane; for 5h; Heating;

DOI:10.1246/bcsj.53.3615

Reference yield:

5-acetoxyhexyl phenyl sulfide (77657-99-9) → (1SR,2RS)-1-methyl-2-phenylthiocyclopentanol (101704-30-7,101704-35-2,125334-92-1,125334-93-2) + (1RS,2RS)-1-methyl-2-phenylthiocyclopentanol (101704-30-7,101704-35-2,125334-92-1,125334-93-2)

Guidance literature:

With N-chloro-succinimide; methyllithium; Yield given. Multistep reaction. Yields of byproduct given; 1.) CCl₄, 2.) THF, -80 deg C, allowed to warm to RT;

DOI:10.1016/S0040-4039(00)88936-4

upstream raw materials:

sodium thiophenolate

5-acetoxy-1-bromohexane

Downstream raw materials:

(1SR,2RS)-1-methyl-2-phenylthiocyclopentanol

(1RS,2RS)-1-methyl-2-phenylthiocyclopentanol

6-phenylthio-2-hexanol