(amino-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2 acetate d'ethyle

Base Information

• Chemical Name: (amino-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2 acetate d'ethyle
• CAS No.: 68672-61-7
• Molecular Formula: C₂₈H₂₆N₄O₄S
• Molecular Weight: 514.605
• Mol file: 68672-61-7.mol

Synonyms:(amino-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2 acetate d'ethyle

Chemical Property of (amino-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2 acetate d'ethyle

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (amino-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2 acetate d'ethyle

There total 3 articles about (amino-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2 acetate d'ethyle which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

(carboxy methoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2 acetate d'ethyle (73599-77-6) → (amino-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2 acetate d'ethyle (68672-61-7)

Guidance literature:

With 4-methyl-morpholine; ammonia; isobutyl chloroformate; In tetrahydrofuran; at -20 ℃;

Reference yield:

(ethoxy-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2 acetate d'ethyle (68672-60-6) → (amino-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2 acetate d'ethyle (68672-61-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / sodium hydroxide / dioxane / 1 h / Ambient temperature

2: 93 percent / isobutyl chloroformate, N-methylmorpholine, ammonia / tetrahydrofuran / -20 °C

With 4-methyl-morpholine; sodium hydroxide; ammonia; isobutyl chloroformate; In tetrahydrofuran; 1,4-dioxane;

Reference yield:

ethyl (Z)-2-(2-triphenylmethylaminothiazol-4-yl)-2-(hydroxyimino)acetate hydrochloride (66339-00-2) → (amino-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2 acetate d'ethyle (68672-61-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 70 percent / potassium carbonate / dimethylformamide / 1.5 h / Ambient temperature

2: 90 percent / sodium hydroxide / dioxane / 1 h / Ambient temperature

3: 93 percent / isobutyl chloroformate, N-methylmorpholine, ammonia / tetrahydrofuran / -20 °C

With 4-methyl-morpholine; sodium hydroxide; ammonia; potassium carbonate; isobutyl chloroformate; In tetrahydrofuran; 1,4-dioxane; N,N-dimethyl-formamide;

upstream raw materials:

(carboxy methoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2 acetate d'ethyle

(ethoxy-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2 acetate d'ethyle

ethyl (Z)-2-(2-triphenylmethylaminothiazol-4-yl)-2-(hydroxyimino)acetate hydrochloride

Downstream raw materials:

acide (amino-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2 acetique

ester de tert-butylique de l'acide (acetoxy methyl)-3(<<(amino-2 oxo-2 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2>-acetyl>-amino)-7 β cepheme-3 carboxylique-4