diisopropylsilyl 4-methoxybenzyl ether

Base Information

• Chemical Name: diisopropylsilyl 4-methoxybenzyl ether
• CAS No.: 1075737-54-0
• Molecular Formula: C₁₄H₂₄O₂Si
• Molecular Weight: 252.429
• Mol file: 1075737-54-0.mol

Synonyms:diisopropylsilyl 4-methoxybenzyl ether

Chemical Property of diisopropylsilyl 4-methoxybenzyl ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diisopropylsilyl 4-methoxybenzyl ether

There total 2 articles about diisopropylsilyl 4-methoxybenzyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

chlorodiisopropylsilane (2227-29-4) + 4-Methoxybenzyl alcohol (105-13-5) → diisopropylsilyl 4-methoxybenzyl ether (1075737-54-0)

Guidance literature:

With 1H-imidazole; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1016/j.tetlet.2008.08.043

Reference yield:

di-isopropylsilane (18209-66-0) + methyl 4-methoxybenzoate (121-98-2) → diisopropylsilyl 4-methoxybenzyl ether (1075737-54-0)

Guidance literature:

With chlorobis(cyclooctene)-iridium(I) dimer; In dichloromethane; at 80 ℃; for 48h; Inert atmosphere;

DOI:10.1021/acs.joc.5b00564

Reference yield: 80.0%

diisopropylsilyl 4-methoxybenzyl ether (1075737-54-0) + phenylacetylene (536-74-3) → (E)-diisopropyl(2-phenylethenyl)silyl 4-methoxybenzyl ether (1132641-43-0)

Guidance literature:

With chloroplatinic acid 1,1,3,3-tetramethyl-1,3-divinyldisiloxane complex; 2,8,9-tris(2-methylpropyl)-2,5,8,9-tetraaza-1-phosphabicyclo[3.3.3]undecane; In tetrahydrofuran; 5,5-dimethyl-1,3-cyclohexadiene; for 2h; stereoselective reaction; Reflux;

DOI:10.1016/j.tetlet.2008.08.043

upstream raw materials:

chlorodiisopropylsilane

4-Methoxybenzyl alcohol

di-isopropylsilane

methyl 4-methoxybenzoate

Downstream raw materials:

(E)-diisopropyl(2-phenylethenyl)silyl 4-methoxybenzyl ether

Refernces

• 1、 Hua, Yuanda,Jung, Seongjeong,Roh, James,Jeon, Junha. "Modular approach to reductive Csp2-H and Csp3-H silylation of carboxylic acid derivatives through single-pot, sequential transition metal catalysis". . p. 4661 - 4671. Retrieved 2015/05/13.