2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl-1-(2R/S)-glycerol

Base Information

• Chemical Name: 2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl-1-(2R/S)-glycerol
• CAS No.: 366477-52-3
• Molecular Formula: C₃₇H₄₂O₈
• Molecular Weight: 614.736
• Mol file: 366477-52-3.mol

Synonyms:2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl-1-(2R/S)-glycerol

Chemical Property of 2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl-1-(2R/S)-glycerol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl-1-(2R/S)-glycerol

There total 2 articles about 2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl-1-(2R/S)-glycerol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

2-propenyl 2,3,4,6-tetra-O-benzyl-α-D-glactopyranoside (112344-80-6) → 2,3,4,6-tetra-O-benzyl-D-galactopyranose (6386-24-9) + 2,3,4,6-tetra-O-benzyl-D-galactonolactone (82598-84-3) + 2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl-1-(2R/S)-glycerol (366477-52-3)

Guidance literature:

With osmium(VIII) oxide; tetrabutylammonium periodite; 4-methylmorpholine N-oxide; In 1,4-dioxane; at 50 ℃; for 120h;

DOI:10.1021/ol016278t

Reference yield:

2-propenyl 2,3,4,6-tetra-O-benzyl-α-D-glactopyranoside (112344-80-6) → 2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl-1-(2R/S)-glycerol (366477-52-3)

Guidance literature:

2-propenyl 2,3,4,6-tetra-O-benzyl-α-D-glactopyranoside; With 4-methylmorpholine N-oxide; osmium(VIII) oxide; In water; acetone; for 23h;

With sodium thiosulfate; In water; acetone;

Reference yield: 48.0%

2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl-1-(2R/S)-glycerol (366477-52-3) → 2-O-benzoyl-1-O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)glycerol (852395-80-3) + 2-di-O-benzoyl-1-O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)glycerol (852395-81-4)

Guidance literature:

2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl-1-(2R/S)-glycerol; With pyridine; trityl chloride; at 100 ℃; for 3h;

With pyridine; benzoyl chloride; at 0 - 20 ℃; for 3h;

With toluene-4-sulfonic acid; In methanol; dichloromethane; at 20 ℃; for 20h;

upstream raw materials:

2-propenyl 2,3,4,6-tetra-O-benzyl-α-D-glactopyranoside

Downstream raw materials:

2-O-benzoyl-1-O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)glycerol

2-di-O-benzoyl-1-O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)glycerol