Technology Process of C20H28O6
There total 10 articles about C20H28O6 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrabutyl ammonium fluoride;
In
tetrahydrofuran;
at 0 ℃;
for 0.0833333h;
optical yield given as %de;
DOI:10.1021/ol202515x
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / -78 - -45 °C
1.2: -45 - 20 °C
2.1: sodium hydride / tetrahydrofuran; mineral oil / 0 - 20 °C
2.2: 0 - 20 °C
3.1: diisobutylaluminium hydride / dichloromethane / 1 h / -78 °C
4.1: manganese(IV) oxide / dichloromethane / 0.5 h / 20 °C
5.1: N-(p-toluenesulfonyl)-L-valine; borane-THF / tetrahydrofuran; dichloromethane / 0.17 h / -78 °C
6.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.08 h / 0 °C
With
N-(p-toluenesulfonyl)-L-valine; manganese(IV) oxide; borane-THF; oxalyl dichloride; tetrabutyl ammonium fluoride; sodium hydride; diisobutylaluminium hydride; dimethyl sulfoxide;
In
tetrahydrofuran; dichloromethane; mineral oil;
1.1: Swern oxidation / 1.2: Swern oxidation / 2.2: Wittig-Horner olefination / 5.1: Kiyooka Aldol Reaction;
DOI:10.1021/ol202515x
- Guidance literature:
-
Multi-step reaction with 3 steps
1: manganese(IV) oxide / dichloromethane / 0.5 h / 20 °C
2: N-(p-toluenesulfonyl)-L-valine; borane-THF / tetrahydrofuran; dichloromethane / 0.17 h / -78 °C
3: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.08 h / 0 °C
With
N-(p-toluenesulfonyl)-L-valine; manganese(IV) oxide; borane-THF; tetrabutyl ammonium fluoride;
In
tetrahydrofuran; dichloromethane;
2: Kiyooka Aldol Reaction;
DOI:10.1021/ol202515x
