Phenyl-methanesulfinic acid (S)-2-hydroxy-1,1-diphenyl-propyl ester

Base Information

Chemical Name:Phenyl-methanesulfinic acid (S)-2-hydroxy-1,1-diphenyl-propyl ester
CAS No.:135790-15-7
Molecular Formula:C₂₂H₂₂O₃S
Molecular Weight:366.481
Hs Code.:

Synonyms:Phenyl-methanesulfinic acid (S)-2-hydroxy-1,1-diphenyl-propyl ester

Suppliers and Price of Phenyl-methanesulfinic acid (S)-2-hydroxy-1,1-diphenyl-propyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Phenyl-methanesulfinic acid (S)-2-hydroxy-1,1-diphenyl-propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Phenyl-methanesulfinic acid (S)-2-hydroxy-1,1-diphenyl-propyl ester

There total 2 articles about Phenyl-methanesulfinic acid (S)-2-hydroxy-1,1-diphenyl-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 126577-49-9
(2R,5S)-trans-4,4-diphenyl-5-methyl-1,3,2-dioxathiolane 2-oxide

: 6921-34-2
benzylmagnesium chloride

: 135790-15-7
Phenyl-methanesulfinic acid (S)-2-hydroxy-1,1-diphenyl-propyl ester

: 135790-18-0
Phenyl-methanesulfinic acid (S)-2-hydroxy-1-methyl-2,2-diphenyl-ethyl ester

Guidance literature:: In tetrahydrofuran; at -78 ℃; Yields of byproduct given;
DOI:10.1021/jo00021a008

Reference yield:

: 46755-94-6
(S)-1,1-diphenyl-1,2-propanediol

: 135790-15-7
Phenyl-methanesulfinic acid (S)-2-hydroxy-1,1-diphenyl-propyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / SOCl₂, triethylamine / CH₂Cl₂ / -40 °C

2: 50 percent / tetrahydrofuran / -78 °C

With thionyl chloride; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo00021a008