[(S,S)-bis(α-methylbenzyl)amino]phosphorous dichloride

Base Information

• Chemical Name: [(S,S)-bis(α-methylbenzyl)amino]phosphorous dichloride
• CAS No.: 777067-25-1
• Molecular Formula: C₁₆H₁₈Cl₂NP
• Molecular Weight: 326.205
• Mol file: 777067-25-1.mol

Synonyms:[(S,S)-bis(α-methylbenzyl)amino]phosphorous dichloride

Chemical Property of [(S,S)-bis(α-methylbenzyl)amino]phosphorous dichloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [(S,S)-bis(α-methylbenzyl)amino]phosphorous dichloride

There total 2 articles about [(S,S)-bis(α-methylbenzyl)amino]phosphorous dichloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(1S,1'S)-bis(1-phenylethyl)amine (21003-56-5,21003-57-6,23294-41-9,42287-48-9,56210-72-1,10024-74-5) → [(S,S)-bis(α-methylbenzyl)amino]phosphorous dichloride (777067-25-1)

Guidance literature:

With n-butyllithium; phosphorus trichloride; In tetrahydrofuran; hexane; at -78 - 20 ℃;

DOI:10.1002/ejoc.200400227

Reference yield:

lithium (S,S)-bis(α-methylbenzyl)amide (197387-11-4) → [(S,S)-bis(α-methylbenzyl)amino]phosphorous dichloride (777067-25-1)

Guidance literature:

With phosphorus trichloride; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 12h; Inert atmosphere; Schlenk technique;

DOI:10.1039/d1cc05576c

Reference yield: 85.0%

C36H24O2 + [(S,S)-bis(α-methylbenzyl)amino]phosphorous dichloride (777067-25-1) → C76H56NO2P

Guidance literature:

C₃₆H₂₄O₂; With sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; for 0.0833333h; Inert atmosphere;

[(S,S)-bis(α-methylbenzyl)amino]phosphorous dichloride; In tetrahydrofuran; mineral oil; at 20 ℃; for 0.25h; Inert atmosphere;

DOI:10.1002/chem.201504658

upstream raw materials:

(1S,1'S)-bis(1-phenylethyl)amine

lithium (S,S)-bis(α-methylbenzyl)amide

Downstream raw materials:

((P)-bis-naphthaleno[1,2-f;2,1-d]-1,3-dioxa-2-phosphacycloheptan-2-yl)-(S,S)-bis(1-phenylethyl)amine

((M)-bis-naphthaleno[1,2-f;2,1-d]-1,3-dioxa-2-phosphacycloheptan-2-yl)-(S,S)-bis(1-phenylethyl)amine

N,N-bis-[(S)-1-phenylethyl]dibenzo[d,f][1,3,2]dioxaphosphepin-6-amine

dixylyl-N,N-bis-((S,S)-1-phenyl-ethyl)phosphinamine