ethyl 7-(((4-(2-perfluoroctylethyl)benzyl)oxy)amino)heptanoate hydrochloride

Base Information

• Chemical Name: ethyl 7-(((4-(2-perfluoroctylethyl)benzyl)oxy)amino)heptanoate hydrochloride
• CAS No.: 1313585-79-3
• Molecular Formula: C₂₆H₂₈F₁₇NO₃*ClH
• Molecular Weight: 761.947
• Mol file: 1313585-79-3.mol

Synonyms:ethyl 7-(((4-(2-perfluoroctylethyl)benzyl)oxy)amino)heptanoate hydrochloride

Chemical Property of ethyl 7-(((4-(2-perfluoroctylethyl)benzyl)oxy)amino)heptanoate hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 7-(((4-(2-perfluoroctylethyl)benzyl)oxy)amino)heptanoate hydrochloride

There total 5 articles about ethyl 7-(((4-(2-perfluoroctylethyl)benzyl)oxy)amino)heptanoate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

ethyl 7-(tert-butoxycarbonyl(4-(2-perfluoroctylethyl)benzyloxy)amino)heptanoate (1313585-47-5) → ethyl 7-(((4-(2-perfluoroctylethyl)benzyl)oxy)amino)heptanoate hydrochloride (1313585-79-3)

Guidance literature:

With ethanol; acetyl chloride; at 20 ℃; for 48h; Inert atmosphere;

DOI:10.1016/j.tet.2011.05.039

Reference yield:

1-(bromomethyl)-4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)benzene → ethyl 7-(((4-(2-perfluoroctylethyl)benzyl)oxy)amino)heptanoate hydrochloride (1313585-79-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / -5 - 20 °C / Inert atmosphere; Darkness

2: caesium carbonate / acetonitrile / 3 h / 45 °C

3: ethanol; acetyl chloride / 48 h / 20 °C / Inert atmosphere

With ethanol; caesium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; acetyl chloride; In tetrahydrofuran; acetonitrile;

DOI:10.1016/j.tet.2011.05.039

Reference yield:

tert-butyl 4-(2-perfluoroctylethyl)benzyloxycarbamate (1313585-45-3) → ethyl 7-(((4-(2-perfluoroctylethyl)benzyl)oxy)amino)heptanoate hydrochloride (1313585-79-3)

Guidance literature:

Multi-step reaction with 2 steps

1: caesium carbonate / acetonitrile / 3 h / 45 °C

2: ethanol; acetyl chloride / 48 h / 20 °C / Inert atmosphere

With ethanol; caesium carbonate; acetyl chloride; In acetonitrile;

DOI:10.1016/j.tet.2011.05.039

upstream raw materials:

ethyl 7-(tert-butoxycarbonyl(4-(2-perfluoroctylethyl)benzyloxy)amino)heptanoate

tert-butyl 4-(2-perfluoroctylethyl)benzyloxycarbamate

ethyl 7-bromoheptanoate

(4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)phenyl)methanol

Downstream raw materials:

2-((7-ethoxy-7-oxoheptyl)amino)-2-(4-isopropylphenyl)acetic acid

7-aminoheptanoic acid ethyl ester

C₃₈H₄₂F₁₇NO₅

C₃₇H₄₀F₁₇NO₅