3-(2-trimethylsilanylethoxycarbonylamino)benzoic acid tert-butyl ester

Base Information

• Chemical Name: 3-(2-trimethylsilanylethoxycarbonylamino)benzoic acid tert-butyl ester
• CAS No.: 1257310-83-0
• Molecular Formula: C₁₇H₂₇NO₄Si
• Molecular Weight: 337.491
• Mol file: 1257310-83-0.mol

Synonyms:3-(2-trimethylsilanylethoxycarbonylamino)benzoic acid tert-butyl ester

Chemical Property of 3-(2-trimethylsilanylethoxycarbonylamino)benzoic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(2-trimethylsilanylethoxycarbonylamino)benzoic acid tert-butyl ester

There total 1 articles about 3-(2-trimethylsilanylethoxycarbonylamino)benzoic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

tert-butyl 3-bromobenzoate (69038-74-0) + carbamic acid 2-trimethylsilylethyl ester (3124-37-6) → 3-(2-trimethylsilanylethoxycarbonylamino)benzoic acid tert-butyl ester (1257310-83-0)

Guidance literature:

With palladium diacetate; caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; at 100 ℃; for 15h; Inert atmosphere; Sealed;

DOI:10.1016/j.tetlet.2010.08.100

Reference yield: 98.0%

3-(2-trimethylsilanylethoxycarbonylamino)benzoic acid tert-butyl ester (1257310-83-0) → tert-butyl 3-aminobenzoate (92146-82-2)

Guidance literature:

With cesium fluoride; In N,N-dimethyl-formamide; at 45 ℃; for 8h;

DOI:10.1016/j.tetlet.2010.08.100

upstream raw materials:

tert-butyl 3-bromobenzoate

carbamic acid 2-trimethylsilylethyl ester

Downstream raw materials:

tert-butyl 3-aminobenzoate