tert-butyl 4-(4-bromo-2,6-dimethylphenylthio)-5H-pyrrolo[3,2-d]pyrimidin-2-yl-4-cyanophenylcarbamate

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Chemical Name:tert-butyl 4-(4-bromo-2,6-dimethylphenylthio)-5H-pyrrolo[3,2-d]pyrimidin-2-yl-4-cyanophenylcarbamate
CAS No.:1164100-76-8
Molecular Formula:C₂₆H₂₄BrN₅O₂S
Molecular Weight:550.479
Hs Code.:

Synonyms:tert-butyl 4-(4-bromo-2,6-dimethylphenylthio)-5H-pyrrolo[3,2-d]pyrimidin-2-yl-4-cyanophenylcarbamate

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Chemical Property of tert-butyl 4-(4-bromo-2,6-dimethylphenylthio)-5H-pyrrolo[3,2-d]pyrimidin-2-yl-4-cyanophenylcarbamate

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Technology Process of tert-butyl 4-(4-bromo-2,6-dimethylphenylthio)-5H-pyrrolo[3,2-d]pyrimidin-2-yl-4-cyanophenylcarbamate

There total 1 articles about tert-butyl 4-(4-bromo-2,6-dimethylphenylthio)-5H-pyrrolo[3,2-d]pyrimidin-2-yl-4-cyanophenylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1164100-75-7
tert-butyl 4-(4-bromo-2,6-dimethylphenylthio)-6-((E)-2-(dimethylamino)vinyl)-5-nitropyrimidin-2-yl-4-cyanophenylcarbamate

: 1164100-76-8
tert-butyl 4-(4-bromo-2,6-dimethylphenylthio)-5H-pyrrolo[3,2-d]pyrimidin-2-yl-4-cyanophenylcarbamate

Guidance literature:: With sodium dithionite; In tetrahydrofuran; water; at 20 ℃; for 48h;

Reference yield:

: 1164100-76-8
tert-butyl 4-(4-bromo-2,6-dimethylphenylthio)-5H-pyrrolo[3,2-d]pyrimidin-2-yl-4-cyanophenylcarbamate

: 74-88-4
methyl iodide

: 1164100-77-9
tert-butyl 4-(4-bromo-2,6-dimethylphenylthio)-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-2-yl-4-cyanophenylcarbamate

Guidance literature:: tert-butyl 4-(4-bromo-2,6-dimethylphenylthio)-5H-pyrrolo[3,2-d]pyrimidin-2-yl-4-cyanophenylcarbamate; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 - 0 ℃; for 2h;

methyl iodide; In tetrahydrofuran; at -78 - 20 ℃; for 4h;