(4R)-3-[(2R)-3-cyclohexylidene-2-methylpropanoyl]-4-phenyl-1,3-oxazolidin-2-one

Base Information

Chemical Name:(4R)-3-[(2R)-3-cyclohexylidene-2-methylpropanoyl]-4-phenyl-1,3-oxazolidin-2-one
CAS No.:1257510-87-4
Molecular Formula:C₁₉H₂₃NO₃
Molecular Weight:313.397
Hs Code.:

Synonyms:(4R)-3-[(2R)-3-cyclohexylidene-2-methylpropanoyl]-4-phenyl-1,3-oxazolidin-2-one

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4R)-3-[(2R)-3-cyclohexylidene-2-methylpropanoyl]-4-phenyl-1,3-oxazolidin-2-one

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Technology Process of (4R)-3-[(2R)-3-cyclohexylidene-2-methylpropanoyl]-4-phenyl-1,3-oxazolidin-2-one

There total 1 articles about (4R)-3-[(2R)-3-cyclohexylidene-2-methylpropanoyl]-4-phenyl-1,3-oxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1257510-85-2
(4R)-3-(3-cyclohexylidenepropanoyl)-4-phenyl-1,3-oxazolidin-2-one

: 74-88-4
methyl iodide

: 1257510-87-4
(4R)-3-[(2R)-3-cyclohexylidene-2-methylpropanoyl]-4-phenyl-1,3-oxazolidin-2-one

: (4R)-3-[(2S)-3-cyclohexylidene-2-methylpropanoyl]-4-phenyl-1,3-oxazolidin-2-one

Guidance literature:: (4R)-3-(3-cyclohexylidenepropanoyl)-4-phenyl-1,3-oxazolidin-2-one; With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium diisopropyl amide; In tetrahydrofuran; hexane; at -78 - -15 ℃; Inert atmosphere;

methyl iodide; In tetrahydrofuran; hexane; at -78 ℃; optical yield given as %de; Inert atmosphere;
DOI:10.1002/ejoc.201000376

Reference yield: 91.0%

: 1257510-87-4
(4R)-3-[(2R)-3-cyclohexylidene-2-methylpropanoyl]-4-phenyl-1,3-oxazolidin-2-one

: 1257510-91-0
(2R)-3-cyclohexylidene-2-methylpropanoic acid

Guidance literature:: With dihydrogen peroxide; lithium hydroxide; In tetrahydrofuran; water; at 0 ℃; for 3.5h; Inert atmosphere;
DOI:10.1002/ejoc.201000376