Technology Process of methyl 2,3,6-tri-O-benzyl-4-deoxy-4-C-[(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)(hydroxy)methyl]-α-D-mannopyranoside
There total 8 articles about methyl 2,3,6-tri-O-benzyl-4-deoxy-4-C-[(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)(hydroxy)methyl]-α-D-mannopyranoside which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
samarium diiodide;
In
tetrahydrofuran;
at 20 ℃;
for 0.166667h;
DOI:10.1021/jo020585a
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: 71 percent / tetrahydrofuran / Heating
2.1: 79 percent / dilauroyl peroxide / benzene / Heating
3.1: MeOH; NaOMe / 5 h / 20 °C
4.1: 367 mg / NaH / dimethylformamide / 0 °C
5.1: 91 percent / potassium carbonate / rhodium trichloride trihydrate / aq. ethanol / 2.5 h / Heating
6.1: ozone / CH2Cl2; methanol / -78 °C
6.2: 85 percent / triphenylphosphine / CH2Cl2; methanol / 1.17 h / -78 - 20 °C
7.1: 55 percent / samarium diiodide / tetrahydrofuran / 0.17 h / 20 °C
With
methanol; samarium diiodide; dilauryl peroxide; sodium methylate; sodium hydride; potassium carbonate; ozone;
rhodium(III) chloride;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide; benzene;
DOI:10.1021/jo020585a
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 367 mg / NaH / dimethylformamide / 0 °C
2.1: 91 percent / potassium carbonate / rhodium trichloride trihydrate / aq. ethanol / 2.5 h / Heating
3.1: ozone / CH2Cl2; methanol / -78 °C
3.2: 85 percent / triphenylphosphine / CH2Cl2; methanol / 1.17 h / -78 - 20 °C
4.1: 55 percent / samarium diiodide / tetrahydrofuran / 0.17 h / 20 °C
With
samarium diiodide; sodium hydride; potassium carbonate; ozone;
rhodium(III) chloride;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo020585a