(3R, 5S)-1-[6-[(4-bromo-2-fluorophenyl)sulfonyl]-5-(methyloxy)-2-pyridinyl]-3,5-dimethylpiperazine

Base Information

Chemical Name:(3R, 5S)-1-[6-[(4-bromo-2-fluorophenyl)sulfonyl]-5-(methyloxy)-2-pyridinyl]-3,5-dimethylpiperazine
CAS No.:952289-12-2
Molecular Formula:C₁₈H₂₂BrFN₄O₃S
Molecular Weight:473.366
Hs Code.:

Synonyms:(3R, 5S)-1-[6-[(4-bromo-2-fluorophenyl)sulfonyl]-5-(methyloxy)-2-pyridinyl]-3,5-dimethylpiperazine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (3R, 5S)-1-[6-[(4-bromo-2-fluorophenyl)sulfonyl]-5-(methyloxy)-2-pyridinyl]-3,5-dimethylpiperazine

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Technology Process of (3R, 5S)-1-[6-[(4-bromo-2-fluorophenyl)sulfonyl]-5-(methyloxy)-2-pyridinyl]-3,5-dimethylpiperazine

There total 1 articles about (3R, 5S)-1-[6-[(4-bromo-2-fluorophenyl)sulfonyl]-5-(methyloxy)-2-pyridinyl]-3,5-dimethylpiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 216159-03-4
4-bromo-2-fluorobenzenesulfonyl chloride

: 952289-02-0
6-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-3-(methyloxy)-2-pyridinamine

: 952289-12-2
(3R, 5S)-1-[6-[(4-bromo-2-fluorophenyl)sulfonyl]-5-(methyloxy)-2-pyridinyl]-3,5-dimethylpiperazine

Guidance literature:: In DCM; at 0 - 20 ℃;

Reference yield:

: 952289-12-2
(3R, 5S)-1-[6-[(4-bromo-2-fluorophenyl)sulfonyl]-5-(methyloxy)-2-pyridinyl]-3,5-dimethylpiperazine

: 338998-93-9
4,4,5,5-tetramethyl-2-(5-methylfuran-2-yl)-1,3,2-dioxaborolane

: 952289-55-3
C₂₃H₂₇FN₄O₄S

Guidance literature:: With sodium carbonate; bis-triphenylphosphine-palladium(II) chloride; In 1,2-dimethoxyethane; water; at 120 ℃; for 0.166667h; Microwave;