1-(N,N-dimethylaminosulfonyl)-1H-1,2,4-triazole-3-sulfonyl chloride

Base Information

• Chemical Name: 1-(N,N-dimethylaminosulfonyl)-1H-1,2,4-triazole-3-sulfonyl chloride
• CAS No.: 171967-86-5
• Molecular Formula: C₄H₇ClN₄O₄S₂
• Molecular Weight: 274.709
• Mol file: 171967-86-5.mol

Synonyms:1-(N,N-dimethylaminosulfonyl)-1H-1,2,4-triazole-3-sulfonyl chloride

Chemical Property of 1-(N,N-dimethylaminosulfonyl)-1H-1,2,4-triazole-3-sulfonyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 1-(N,N-dimethylaminosulfonyl)-1H-1,2,4-triazole-3-sulfonyl chloride

There total 1 articles about 1-(N,N-dimethylaminosulfonyl)-1H-1,2,4-triazole-3-sulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.1%

3-((1-(N,N-dimethylaminosulfonyl)-1H-1,2,4-triazol-3-yl)disulfanyl)-N,N-dimethyl-1H-1,2,4-triazole-1-sulfonamide (247236-09-5) → 1-(N,N-dimethylaminosulfonyl)-1H-1,2,4-triazole-3-sulfonyl chloride (171967-86-5)

Guidance literature:

With chlorine; In methanol; water; 1,2-dichloro-ethane;

Reference yield: 86.0%

1-(N,N-dimethylaminosulfonyl)-1H-1,2,4-triazole-3-sulfonyl chloride (171967-86-5) + 4-(2'-cyanophenoxy)phenol → C17H15N5O6S2

Guidance literature:

4-(2'-cyanophenoxy)phenol; With sodium hydride; In 1,2-dimethoxyethane; mineral oil; for 1h;

1-(N,N-dimethylaminosulfonyl)-1H-1,2,4-triazole-3-sulfonyl chloride; In 1,2-dimethoxyethane; mineral oil; at 25 ℃; Cooling with ice;

Reference yield: 78.0%

1-(N,N-dimethylaminosulfonyl)-1H-1,2,4-triazole-3-sulfonyl chloride (171967-86-5) + C10H11BrFN (1016706-75-4) → N3-[(2-bromo-4-fluorophenyl)methyl]-N3-cyclopropyl-N1,N1-dimethyl-1H-1,2,4-triazole-1,3-disulfonamide

Guidance literature:

With pyridine; In tetrahydrofuran; at 0 - 20 ℃; for 2.17h;

DOI:10.1021/acs.jafc.9b07887

upstream raw materials:

3-((1-(N,N-dimethylaminosulfonyl)-1H-1,2,4-triazol-3-yl)disulfanyl)-N,N-dimethyl-1H-1,2,4-triazole-1-sulfonamide

Downstream raw materials:

1-(N,N-dimethylsulfamoyl)-3-(3-phenyl-4-chloro-5-methylpyrazol-1-yl)sulfonyl-1,2,4-triazole

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