benzyl (2S,3R,6S,8S)-8-{(2R,3R,6S,7R,8S,9R,10R,13S,15R)-8-tert-butyldimethylsilyloxy-3,6;10,13-bis-epoxy-15-(N-tert-butyloxycarbonyl-N-methylamino)-2,7,9-trimethyloctadecanoyloxy}-3,6-epoxy-2-methylundecanoate

Base Information

Chemical Name:benzyl (2S,3R,6S,8S)-8-{(2R,3R,6S,7R,8S,9R,10R,13S,15R)-8-tert-butyldimethylsilyloxy-3,6;10,13-bis-epoxy-15-(N-tert-butyloxycarbonyl-N-methylamino)-2,7,9-trimethyloctadecanoyloxy}-3,6-epoxy-2-methylundecanoate
CAS No.:364597-71-7
Molecular Formula:C₅₂H₈₉NO₁₀Si
Molecular Weight:916.365
Hs Code.:

benzyl (2S,3R,6S,8S)-8-{(2R,3R,6S,7R,8S,9R,10R,13S,15R)-8-tert-butyldimethylsilyloxy-3,6;10,13-bis-epoxy-15-(N-tert-butyloxycarbonyl-N-methylamino)-2,7,9-trimethyloctadecanoyloxy}-3,6-epoxy-2-methylundecanoate

Synonyms:benzyl (2S,3R,6S,8S)-8-{(2R,3R,6S,7R,8S,9R,10R,13S,15R)-8-tert-butyldimethylsilyloxy-3,6;10,13-bis-epoxy-15-(N-tert-butyloxycarbonyl-N-methylamino)-2,7,9-trimethyloctadecanoyloxy}-3,6-epoxy-2-methylundecanoate

Suppliers and Price of benzyl (2S,3R,6S,8S)-8-{(2R,3R,6S,7R,8S,9R,10R,13S,15R)-8-tert-butyldimethylsilyloxy-3,6;10,13-bis-epoxy-15-(N-tert-butyloxycarbonyl-N-methylamino)-2,7,9-trimethyloctadecanoyloxy}-3,6-epoxy-2-methylundecanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of benzyl (2S,3R,6S,8S)-8-{(2R,3R,6S,7R,8S,9R,10R,13S,15R)-8-tert-butyldimethylsilyloxy-3,6;10,13-bis-epoxy-15-(N-tert-butyloxycarbonyl-N-methylamino)-2,7,9-trimethyloctadecanoyloxy}-3,6-epoxy-2-methylundecanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of benzyl (2S,3R,6S,8S)-8-{(2R,3R,6S,7R,8S,9R,10R,13S,15R)-8-tert-butyldimethylsilyloxy-3,6;10,13-bis-epoxy-15-(N-tert-butyloxycarbonyl-N-methylamino)-2,7,9-trimethyloctadecanoyloxy}-3,6-epoxy-2-methylundecanoate

There total 36 articles about benzyl (2S,3R,6S,8S)-8-{(2R,3R,6S,7R,8S,9R,10R,13S,15R)-8-tert-butyldimethylsilyloxy-3,6;10,13-bis-epoxy-15-(N-tert-butyloxycarbonyl-N-methylamino)-2,7,9-trimethyloctadecanoyloxy}-3,6-epoxy-2-methylundecanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 364597-69-3
benzyl (2S,3R,6S,8S)-3,6-epoxy-8-hydroxy-2-methylundecanoate

: 364597-56-8
(2R,3R,6S,7R,8S,9R,10R,13S,15R)-8-tert-butyldimethylsilyloxy-3,6;10,13-bis-epoxy-15-(N-tert-butyloxycarbonyl-N-methylamino)-2,7,9-trimethyloctadecanoic acid

: 364597-71-7
benzyl (2S,3R,6S,8S)-8-{(2R,3R,6S,7R,8S,9R,10R,13S,15R)-8-tert-butyldimethylsilyloxy-3,6;10,13-bis-epoxy-15-(N-tert-butyloxycarbonyl-N-methylamino)-2,7,9-trimethyloctadecanoyloxy}-3,6-epoxy-2-methylundecanoate

Guidance literature:: With dmap; 2,4,6-trichlorobenzoyl chloride; In dichloromethane; at 20 ℃; for 3.5h;
DOI:10.1039/c2ob26801a

Reference yield:

: 364597-64-8
(2R,3R,6S,8S)-1-benzyloxy-8-tert-butyldiphenylsilyloxy-3,6-epoxy-2-methylundecane

: 364597-71-7
benzyl (2S,3R,6S,8S)-8-{(2R,3R,6S,7R,8S,9R,10R,13S,15R)-8-tert-butyldimethylsilyloxy-3,6;10,13-bis-epoxy-15-(N-tert-butyloxycarbonyl-N-methylamino)-2,7,9-trimethyloctadecanoyloxy}-3,6-epoxy-2-methylundecanoate

Guidance literature:: Multi-step reaction with 6 steps

1: 70 percent / H₂ / Pd/C

2: Dess-Martin periodane

3: NaOCl₂; NaH₂PO₄

4: (i-Pr)2EtN

5: 49 percent / conc. aq.HCl / methanol

6: 63 percent / 2,4,6-trichlorobenzoyl chloride; DMAP / CH₂Cl₂ / 3 h / 20 °C

With hydrogenchloride; dmap; sodium dihydrogenphosphate; 2,4,6-trichlorobenzoyl chloride; hydrogen; Dess-Martin periodane; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In methanol; dichloromethane; 1: hydrogenolysis;
DOI:10.1016/S0040-4039(01)00921-2

Reference yield:

: 364597-91-1
(2S,3R,6S,7R,8S,9R,10R,13S,15R)-1-benzyloxy-8-tert-butyldimethylsilyloxy-3,6;10,13-bis-epoxy-15-(N-methylamino)-2,7,9-trimethyloctadecane

: 364597-71-7
benzyl (2S,3R,6S,8S)-8-{(2R,3R,6S,7R,8S,9R,10R,13S,15R)-8-tert-butyldimethylsilyloxy-3,6;10,13-bis-epoxy-15-(N-tert-butyloxycarbonyl-N-methylamino)-2,7,9-trimethyloctadecanoyloxy}-3,6-epoxy-2-methylundecanoate

Guidance literature:: Multi-step reaction with 5 steps

1: 80 percent / Et₃N

2: H₂ / Pd/C

3: Dess-Martin periodane

4: NaOCl₂; NaH₂PO₄

5: 63 percent / 2,4,6-trichlorobenzoyl chloride; DMAP / CH₂Cl₂ / 3 h / 20 °C

With dmap; sodium dihydrogenphosphate; 2,4,6-trichlorobenzoyl chloride; hydrogen; Dess-Martin periodane; triethylamine; palladium on activated charcoal; In dichloromethane;
DOI:10.1016/S0040-4039(01)00921-2