Technology Process of C39H54N8O12
There total 6 articles about C39H54N8O12 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C30H42N4O8;
With
toluene-4-sulfonic acid; sodium nitrite;
In
methanol; water;
at 20 ℃;
for 0.5h;
H2N-VGS-CO2H;
In
methanol; aq. phosphate buffer;
at 20 ℃;
for 2h;
pH=7;
DOI:10.1021/ol5016509
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / dichloromethane
2.1: palladium 10% on activated carbon; hydrogen / methanol
3.1: triethylamine / dichloromethane
4.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / dichloromethane
5.1: sodium nitrite; toluene-4-sulfonic acid / methanol; water / 0.5 h / 20 °C
5.2: 2 h / 20 °C / pH 7
With
palladium 10% on activated carbon; hydrogen; benzotriazol-1-ol; toluene-4-sulfonic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; N-ethyl-N,N-diisopropylamine; sodium nitrite;
In
methanol; dichloromethane; water;
DOI:10.1021/ol5016509
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: triethylamine / dichloromethane
2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / dichloromethane
3.1: sodium nitrite; toluene-4-sulfonic acid / methanol; water / 0.5 h / 20 °C
3.2: 2 h / 20 °C / pH 7
With
benzotriazol-1-ol; toluene-4-sulfonic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; N-ethyl-N,N-diisopropylamine; sodium nitrite;
In
methanol; dichloromethane; water;
DOI:10.1021/ol5016509