5-benzyltetrazolylacetic acid

Base Information

Chemical Name:5-benzyltetrazolylacetic acid
CAS No.:99072-90-9
Molecular Formula:C₁₀H₁₀N₄O₂
Molecular Weight:218.215
Hs Code.:

Synonyms:5-benzyltetrazolylacetic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-benzyltetrazolylacetic acid

Chemical Property:

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Technology Process of 5-benzyltetrazolylacetic acid

There total 5 articles about 5-benzyltetrazolylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 18489-25-3
5-benzyl-1H-tetrazole

: 96-32-2
bromoacetic acid methyl ester

: 99072-90-9
5-benzyltetrazolylacetic acid

Guidance literature:: With potassium hydroxide; sodium ethanolate; Yield given. Multistep reaction; 1.) EtOH, reflux, 16 h, 2.) MeOH, reflux, 3 h;
DOI:10.1007/BF00766552

Reference yield:

: 140-29-4
phenylacetonitrile

: 99072-90-9
5-benzyltetrazolylacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 83.5 percent / NaN₃, glacial acetic acid, acetic acid / butan-1-ol / Heating

2: 1.) EtONa, 2.) KOH / 1.) EtOH, reflux, 16 h, 2.) MeOH, reflux, 3 h

With potassium hydroxide; sodium azide; sodium ethanolate; acetic acid; In butan-1-ol;
DOI:10.1007/BF00766552

Reference yield:

: 4838-35-1
N-(phenylacetyl)glycine ethyl ester

: 99072-90-9
5-benzyltetrazolylacetic acid

Guidance literature:: With phosphorus pentachloride; benzene; anschliessenden Erwaermen mit HN₃ und Behandeln des Reaktionsprodukts mit aethanol.KOH;
DOI:10.1021/jo01109a013