Hydrazinecarboxamide, 2-(3-phenyl-2-propenylidene)-N-((4,5,7-trimethyl-2-oxo-2H-1-benzopyran-8-yl)sulfonyl)-

Base Information

• Chemical Name: Hydrazinecarboxamide, 2-(3-phenyl-2-propenylidene)-N-((4,5,7-trimethyl-2-oxo-2H-1-benzopyran-8-yl)sulfonyl)-
• CAS No.: 85302-43-8
• Molecular Formula: C₂₂H₂₁N₃O₅S
• Molecular Weight: 439.492
• Mol file: 85302-43-8.mol

Synonyms:85302-43-8;Hydrazinecarboxamide, 2-(3-phenyl-2-propenylidene)-N-((4,5,7-trimethyl-2-oxo-2H-1-benzopyran-8-yl)sulfonyl)-;LS-76622

Chemical Property of Hydrazinecarboxamide, 2-(3-phenyl-2-propenylidene)-N-((4,5,7-trimethyl-2-oxo-2H-1-benzopyran-8-yl)sulfonyl)-

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.31g/cm³
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 439.12019195
• Heavy Atom Count: 31
• Complexity: 868

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C2=C1C(=CC(=O)O2)C)S(=O)(=O)NC(=O)NN=CC=CC3=CC=CC=C3)C
• Isomeric SMILES: CC1=CC(=C(C2=C1C(=CC(=O)O2)C)S(=O)(=O)NC(=O)N/N=C/C=C/C3=CC=CC=C3)C

Technology Process of Hydrazinecarboxamide, 2-(3-phenyl-2-propenylidene)-N-((4,5,7-trimethyl-2-oxo-2H-1-benzopyran-8-yl)sulfonyl)-

There total 5 articles about Hydrazinecarboxamide, 2-(3-phenyl-2-propenylidene)-N-((4,5,7-trimethyl-2-oxo-2H-1-benzopyran-8-yl)sulfonyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

3-phenyl-propenal (104-55-2) + N4-(4,5,7-trimethyl-8-coumarinylsulphonyl) semicarbazide (85302-40-5) → C22H21N3O5S (85302-43-8)

Guidance literature:

With acetic acid; In ethanol; for 4h; Heating;

Reference yield:

4,5,7-trimethylcoumarin (14002-91-6) → C22H21N3O5S (85302-43-8)

Guidance literature:

Multi-step reaction with 5 steps

1: 60 percent / chlorosulphonic acid / 1.) RT, 30 min; 2.) 80 deg C

2: 80 percent / aq. NH₃ / Heating

3: K₂CO₃ / acetone / 9 h / Heating

4: 60 percent / hydrazine hydrate / ethanol / 8 h / Heating

5: 50 percent / glacial AcOH / ethanol / 4 h / Heating

With chlorosulfonic acid; ammonium hydroxide; potassium carbonate; hydrazine hydrate; acetic acid; In ethanol; acetone;

Reference yield:

4,5,7-trimethyl-8-coumarinylsulphonamide (52415-46-0) → C22H21N3O5S (85302-43-8)

Guidance literature:

Multi-step reaction with 3 steps

1: K₂CO₃ / acetone / 9 h / Heating

2: 60 percent / hydrazine hydrate / ethanol / 8 h / Heating

3: 50 percent / glacial AcOH / ethanol / 4 h / Heating

With potassium carbonate; hydrazine hydrate; acetic acid; In ethanol; acetone;

upstream raw materials:

3-phenyl-propenal

N⁴-(4,5,7-trimethyl-8-coumarinylsulphonyl) semicarbazide

4,5,7-trimethylcoumarin

4,5,7-trimethyl-8-coumarinylsulphonamide