Technology Process of benzyl 4-O-(methyl 2',3',4'-tri-O-acetyl-β-D-glucopyranosyluronate)-2-benzyloxy-6-pentadecanylbenzoate
There total 10 articles about benzyl 4-O-(methyl 2',3',4'-tri-O-acetyl-β-D-glucopyranosyluronate)-2-benzyloxy-6-pentadecanylbenzoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
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Multi-step reaction with 4 steps
1: 99 percent / H2 / Pd/C / ethyl acetate / 5 h / 20 °C / 760 Torr
2: 88 percent / KHCO3 / dimethylformamide / 40 h / Heating
3: Ag2O / acetonitrile / 6 h / 38 °C
4: 112 mg / K2CO3 / acetone / 12 h / Heating
With
hydrogen; potassium carbonate; potassium hydrogencarbonate; silver(l) oxide;
palladium on activated charcoal;
In
ethyl acetate; N,N-dimethyl-formamide; acetone; acetonitrile;
3: Koenigs-Knorr reaction;
DOI:10.1021/jo051384k
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.40 g / KOH / dimethylsulfoxide; H2O / 24 h / 90 °C
2: 99 percent / H2 / Pd/C / ethyl acetate / 5 h / 20 °C / 760 Torr
3: 88 percent / KHCO3 / dimethylformamide / 40 h / Heating
4: Ag2O / acetonitrile / 6 h / 38 °C
5: 112 mg / K2CO3 / acetone / 12 h / Heating
With
potassium hydroxide; hydrogen; potassium carbonate; potassium hydrogencarbonate; silver(l) oxide;
palladium on activated charcoal;
In
water; dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide; acetone; acetonitrile;
4: Koenigs-Knorr reaction;
DOI:10.1021/jo051384k
- Guidance literature:
-
Multi-step reaction with 10 steps
1.1: 4.15 g / NaH2PO4; NaClO2 / dimethylsulfoxide; H2O / 20 °C
2.1: 99 percent / DBU / acetonitrile / 20 °C
3.1: LDA / tetrahydrofuran; hexane / 0.33 h / -78 °C
3.2: 70 percent / tetrahydrofuran; hexane / -78 - 20 °C
4.1: 82 percent / BBr3 / CH2Cl2 / 48 h / -10 °C
5.1: K2CO3 / acetone / 12 h / Heating
6.1: 1.40 g / KOH / dimethylsulfoxide; H2O / 24 h / 90 °C
7.1: 99 percent / H2 / Pd/C / ethyl acetate / 5 h / 20 °C / 760 Torr
8.1: 88 percent / KHCO3 / dimethylformamide / 40 h / Heating
9.1: Ag2O / acetonitrile / 6 h / 38 °C
10.1: 112 mg / K2CO3 / acetone / 12 h / Heating
With
potassium hydroxide; sodium chlorite; sodium dihydrogenphosphate; hydrogen; boron tribromide; potassium carbonate; potassium hydrogencarbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; silver(l) oxide; lithium diisopropyl amide;
palladium on activated charcoal;
In
tetrahydrofuran; hexane; dichloromethane; water; dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide; acetone; acetonitrile;
9.1: Koenigs-Knorr reaction;
DOI:10.1021/jo051384k
