6-bromo-N-[(2,6-dimethylphenyl)methyl]-2-methylimidazo[1,2-a]pyridin-8-amine

Base Information

• Chemical Name: 6-bromo-N-[(2,6-dimethylphenyl)methyl]-2-methylimidazo[1,2-a]pyridin-8-amine
• CAS No.: 910777-50-3
• Molecular Formula: C₁₇H₁₈BrN₃
• Molecular Weight: 344.254

Synonyms:6-bromo-N-[(2,6-dimethylphenyl)methyl]-2-methylimidazo[1,2-a]pyridin-8-amine

Chemical Property of 6-bromo-N-[(2,6-dimethylphenyl)methyl]-2-methylimidazo[1,2-a]pyridin-8-amine

Chemical Property:

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Technology Process of 6-bromo-N-[(2,6-dimethylphenyl)methyl]-2-methylimidazo[1,2-a]pyridin-8-amine

There total 1 articles about 6-bromo-N-[(2,6-dimethylphenyl)methyl]-2-methylimidazo[1,2-a]pyridin-8-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-bromo-2-methylimidazo[1,2-a]pyridin-8-amine (910777-49-0) + 2,6-dimethylbenzyl chloride (5402-60-8) → 6-bromo-N-[(2,6-dimethylphenyl)methyl]-2-methylimidazo[1,2-a]pyridin-8-amine (910777-50-3)

Guidance literature:

With sodium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

Reference yield:

2-hydroxypyridin (142-08-5) + 6-bromo-N-[(2,6-dimethylphenyl)methyl]-2-methylimidazo[1,2-a]pyridin-8-amine (910777-50-3) → 1-(8-([(2,6-dimethylphenyl)methyl]amino)-2-methylimidazo[1,2-a]pyridin-6-yl)-2(1H)-pyridinone

Guidance literature:

With copper(l) iodide; potassium carbonate; In 1-methyl-pyrrolidin-2-one; at 155 ℃; for 0.5h; Microwave irradiation;

Reference yield:

1,2,4-Triazole (288-88-0) + 6-bromo-N-[(2,6-dimethylphenyl)methyl]-2-methylimidazo[1,2-a]pyridin-8-amine (910777-50-3) → N-[(2,6-dimethylphenyl)methyl]-2-methyl-6-(1H-1,2,4-triazol-1-yl)imidazo[1,2-a]pyridin-8-amine

Guidance literature:

With copper(l) iodide; caesium carbonate; In 1-methyl-pyrrolidin-2-one; at 180 ℃; for 16h; Microwave irradiation;

upstream raw materials:

6-bromo-2-methylimidazo[1,2-a]pyridin-8-amine

2,6-dimethylbenzyl chloride

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